A growing preclinical and clinical body of work on the effects of chronic drug use and drug
addiction has extended the scope of inquiry from the putative reward-related subcortical …

The loss of control over drug intake that occurs in addiction was initially believed to result
from disruption of subcortical reward circuits. However, imaging studies in addictive …

Conduct disorder is a childhood behaviour disorder that is characterized by persistent
aggressive or antisocial behaviour that disrupts the child's environment and impairs his or …

Since the first study in stimulant-dependent individuals using structural MRI was published
fifteen years ago, much evidence has accumulated on brain abnormalities associated with …

Context The population of men who display persistent antisocial and violent behavior is
heterogeneous. Callous-unemotional traits in childhood and psychopathic traits in …

Psychopathic individuals identified through contemporary instruments vary considerably in
personality and etiological background, which creates confusion in practice and …

Cocaine, a powerful vasoconstrictor, induces immune responses including cytokine
elevations. Chronic cocaine use is associated with functional brain impairments potentially …

BACKGROUND: Impulsivity is thought to play a key role in cocaine addiction onset and
progression; therefore, we hypothesized that different facets of impulsive personality may be …

During the past two decades, there has been a tremendous expansion of knowledge
regarding the neurobiological effects of substance abuse and how these effects impact …

People diagnosed with neuropsychiatric disorders such as depression, anxiety, addiction or
schizophrenia often have dysregulated memory, mood, pattern separation and/or reward …