Directed evolution: methodologies and applications

Y Wang, P Xue, M Cao, T Yu, ST Lane… - Chemical reviews, 2021 - ACS Publications
Directed evolution aims to expedite the natural evolution process of biological molecules
and systems in a test tube through iterative rounds of gene diversifications and library …

Synthetic biology: bottom-up assembly of molecular systems

S Hirschi, TR Ward, WP Meier, DJ Müller… - Chemical …, 2022 - ACS Publications
The bottom-up assembly of biological and chemical components opens exciting
opportunities to engineer artificial vesicular systems for applications with previously unmet …

Role of biocatalysis in sustainable chemistry

RA Sheldon, JM Woodley - Chemical reviews, 2018 - ACS Publications
Based on the principles and metrics of green chemistry and sustainable development,
biocatalysis is both a green and sustainable technology. This is largely a result of the …

Physiological functions of bacterial “multidrug” efflux pumps

PJF Henderson, C Maher, LDH Elbourne… - Chemical …, 2021 - ACS Publications
Bacterial multidrug efflux pumps have come to prominence in human and veterinary
pathogenesis because they help bacteria protect themselves against the antimicrobials …

The biology of ergothioneine, an antioxidant nutraceutical

I Borodina, LC Kenny, CM McCarthy… - Nutrition Research …, 2020 - cambridge.org
Ergothioneine (ERG) is an unusual thio-histidine betaine amino acid that has potent
antioxidant activities. It is synthesised by a variety of microbes, especially fungi (including in …

Engineering cell membrane‐based nanotherapeutics to target inflammation

H Yan, D Shao, YH Lao, M Li, H Hu… - Advanced …, 2019 - Wiley Online Library
Inflammation is ubiquitous in the body, triggering desirable immune response to defend
against dangerous signals or instigating undesirable damage to cells and tissues to cause …

Recent advances in whole cell biocatalysis techniques bridging from investigative to industrial scale

J Wachtmeister, D Rother - Current opinion in biotechnology, 2016 - Elsevier
Highlights•The use of whole cell biocatalysts is appealing due to their inexpensive
production.•Applications in unconventional media allow high substrate and product …

[HTML][HTML] Bioprocess intensification: A route to efficient and sustainable biocatalytic transformations for the future

KVK Boodhoo, MC Flickinger, JM Woodley… - … and Processing-Process …, 2022 - Elsevier
With the current pressing need to rise to the ambition of net zero targets to mitigate carbon
emissions and climate change impacts, sustainable processing has never been more …

Synthetic and systems biology for microbial production of commodity chemicals

V Chubukov, A Mukhopadhyay, CJ Petzold… - NPJ systems biology …, 2016 - nature.com
The combination of synthetic and systems biology is a powerful framework to study
fundamental questions in biology and produce chemicals of immediate practical application …

[PDF][PDF] Engineering tolerance to industrially relevant stress factors in yeast cell factories

Q Deparis, A Claes, MR Foulquié-Moreno… - FEMS yeast …, 2017 - academic.oup.com
The main focus in development of yeast cell factories has generally been on establishing
optimal activity of heterologous pathways and further metabolic engineering of the host …