Three principal types of chromosomal sex determination are found in nature: male
heterogamety (XY systems, as in mammals), female heterogamety (ZW systems, as in birds) …

The forthcoming massive genome data generated by the Earth BioGenome Project will open
up a new era of comparative genomics, for which genome synteny analysis provides an …

Y chromosomes underlie sex determination in mammals, but their repeat-rich nature has
hampered sequencing and associated evolutionary studies. Here we trace Y evolution …

Background Despite the popularity of zebrafish as a research model, its sex determination
(SD) mechanism is still unknown. Most cytogenetic studies failed to find dimorphic sex …

Heterogeneity in recombination rate may strongly influence genome evolution and entail
methodological challenges to genomic investigation. Nevertheless, a solid understanding of …

Chromosomal inversions evolve frequently but the reasons for this remain unclear. We used
cytological descriptions of 411 species of passerine birds to identify large pericentric …

Mammalian X chromosomes evolved under various mechanisms including sexual
antagonism, the faster-X process, and meiotic sex chromosome inactivation (MSCI). These …

Silene latifolia is a dioecious plant with heteromorphic sex chromosomes that have
originated only∼ 10 million years ago and is a promising model organism to study sex …

Background Y chromosomes are responsible for the initiation of male development, male
fertility, and other male-related functions in diverse species. However, Y genes are rarely …

XWAS is a new software suite for the analysis of the X chromosome in association studies
and similar genetic studies. The X chromosome plays an important role in human disease …