The ego in psychedelic drug action–ego defenses, ego boundaries, and the therapeutic role of regression

T Buchborn, HS Kettner, L Kärtner… - Frontiers in …, 2023 - frontiersin.org
The ego is one of the most central psychological constructs in psychedelic research and a
key factor in psychotherapy, including psychedelic-assisted forms of psychotherapy. Despite …

Psilocybin in palliative care: An update

E Whinkin, M Opalka, C Watters, A Jaffe… - Current Geriatrics …, 2023 - Springer
Abstract Purpose of Review This review article summarizes clinically and socially relevant
developments over the past five years in the therapeutic use of the classical tryptamine …

Culture, context, and ethics in the therapeutic use of hallucinogens: Psychedelics as active super-placebos?

D Dupuis, S Veissière - Transcultural Psychiatry, 2022 - journals.sagepub.com
Following decades of prohibition and widespread concern about their mind-altering
properties, there is increasing public, scholarly, and clinical interest in the therapeutic …

The Montreal model: an integrative biomedical-psychedelic approach to ketamine for severe treatment-resistant depression

N Garel, J Drury, J Thibault Lévesque… - Frontiers in …, 2023 - frontiersin.org
Background Subanesthetic ketamine has accumulated meta-analytic evidence for rapid
antidepressant effects in treatment-resistant depression (TRD), resulting in both excitement …

Psychedelics for treatment resistant depression: are they game changers?

M Kalfas, RH Taylor, D Tsapekos… - Expert opinion on …, 2023 - Taylor & Francis
Introduction A new era of treatment for adults with treatment-resistant depression (TRD),
which involves psychedelic substances, is dawning. Emerging evidence indicates that …

Longitudinal associations between psychedelic use and psychotic symptoms in the United States and the United Kingdom

L Honk, CUD Stenfors, SB Goldberg… - Journal of Affective …, 2024 - Elsevier
It has long been speculated that psychedelic use could provoke the onset of psychosis, but
there is little evidence to support this conjecture. Using a longitudinal research design with …

Content analysis of Reddit posts about coadministration of selective serotonin reuptake inhibitors and psilocybin mushrooms

K Sakai, ER Bradley, JA Zamaria, G Agin-Liebes… - …, 2024 - Springer
Objectives We aimed to explore potential interactions between psilocybin and SSRIs by
characterizing peoples' real-world experiences using psilocybin mushrooms and SSRIs …

On the social epistemology of psychedelic experience

MM Pedersen, A Steglich-Petersen - Philosophical Psychology, 2024 - Taylor & Francis
Both traditional and recent accounts of the beneficial and therapeutic effects of psychedelic
experiences tie these effects to specifically epistemic changes, for example the enabling of …

The ketamine chameleon: history, pharmacology, and the contested value of experience

D Diep, S de la Salle, J Thibault Lévesque… - Expert Review of …, 2025 - Taylor & Francis
Introduction Since its synthesis in 1962, ketamine has been widely used in diverse medical
contexts, from anesthesia to treatment-resistant depression. However, interpretations of …

Psychedelic Therapy: A Primer for Primary Care Clinicians—Psilocybin

BJ Tabaac, K Shinozuka, A Arenas… - American Journal of …, 2024 - journals.lww.com
Background: The primary psychoactive drug in magic mushrooms, psilocybin, induces
profound alterations in consciousness through the 5-HT 2A receptor. This review …