The rise of antimicrobial resistance, particularly from extended-spectrum β-lactamase
producing Enterobacteriaceae (ESBL-E), poses a significant global health challenge as it …

National action plans enumerate many interventions as potential strategies to reduce the
burden of bacterial antimicrobial resistance (AMR). However, knowledge of the benefits …

Antibiotic use is increasing worldwide. However, the use of antibiotics is clearly associated
with changes in gut microbiome composition and function, and perturbations have been …

Background Optimum management of childhood diarrhoea in low-resource settings has
been hampered by insufficient data on aetiology, burden, and associated clinical …

Antimicrobial resistance (AMR) is a growing public health challenge that is expected to
disproportionately burden lower-and middle-income countries (LMICs) in the coming …

Background Antibiotic resistance is a global public health issue, particularly in low-and
middle-income countries (LMICs), where antibiotics required to treat resistant infections are …

Background Antibiotic resistance is a major threat to global health. Although detailed
information about antibiotic use in high-income countries is available, little is known …

Background Despite large reductions in under-5 lower respiratory infection (LRI) mortality in
many locations, the pace of progress for LRIs has generally lagged behind that of other …

Vaccines may reduce the burden of antimicrobial resistance, in part by preventing infections
for which treatment often includes the use of antibiotics,,–. However, the effects of …

Background. Giardia are among the most common enteropathogens detected in children in
low-resource settings. We describe here the epidemiology of infection with Giardia in the first …