All roads lead to the motor cortex: psychomotor mechanisms and their biochemical modulation in psychiatric disorders
Psychomotor abnormalities have been abundantly observed in psychiatric disorders like
major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia (SCH). Although …
major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia (SCH). Although …
[HTML][HTML] Primary motor cortex in Parkinson's disease: Functional changes and opportunities for neurostimulation
Movement abnormalities of Parkinson's disease (PD) arise from disordered neural activity in
multiple interconnected brain structures. The planning and execution of movement requires …
multiple interconnected brain structures. The planning and execution of movement requires …
[HTML][HTML] Short-term plasticity of the motor cortex compensates for bradykinesia in Parkinson's disease
A Guerra, D Colella, A Cannavacciuolo… - Neurobiology of …, 2023 - Elsevier
Patients with Parkinson's disease (PD) show impaired short-term potentiation (STP)
mechanisms in the primary motor cortex (M1). However, the role played by this …
mechanisms in the primary motor cortex (M1). However, the role played by this …
Dysfunction of motor cortices in Parkinson's disease
The cerebral cortex has long been thought to be involved in the pathophysiology of motor
symptoms of Parkinson's disease. The impaired cortical function is believed to be a direct …
symptoms of Parkinson's disease. The impaired cortical function is believed to be a direct …
[HTML][HTML] Cortical beta burst dynamics are altered in Parkinson's disease but normalized by deep brain stimulation
Exaggerated subthalamic beta oscillatory activity and increased beta range cortico-
subthalamic synchrony have crystallized as the electrophysiological hallmarks of …
subthalamic synchrony have crystallized as the electrophysiological hallmarks of …
GABAergic changes in the thalamocortical circuit in Parkinson's disease
Parkinson's disease is characterized by bradykinesia, rigidity, and tremor. These symptoms
have been related to an increased gamma‐aminobutyric acid (GABA) ergic inhibitory drive …
have been related to an increased gamma‐aminobutyric acid (GABA) ergic inhibitory drive …
A systematic review of MEG‐based studies in Parkinson's disease: The motor system and beyond
Parkinson's disease (PD) is accompanied by functional changes throughout the brain,
including changes in the electromagnetic activity recorded with magnetoencephalography …
including changes in the electromagnetic activity recorded with magnetoencephalography …
Modulation of post‐movement beta rebound by contraction force and rate of force development
Movement induced modulation of the beta rhythm is one of the most robust neural oscillatory
phenomena in the brain. In the preparation and execution phases of movement, a loss in …
phenomena in the brain. In the preparation and execution phases of movement, a loss in …
Manganese-induced sex-specific gut microbiome perturbations in C57BL/6 mice
Overexposure to manganese (Mn) leads to toxic effects, such as promoting the development
of Parkinson's-like neurological disorders. The gut microbiome is deeply involved in immune …
of Parkinson's-like neurological disorders. The gut microbiome is deeply involved in immune …
[HTML][HTML] The cortical signature of symptom laterality in Parkinson's disease
E Heinrichs-Graham, PM Santamaria… - NeuroImage: Clinical, 2017 - Elsevier
Patients with Parkinson's disease (PD) often present with unilateral motor symptoms that
eventually spread to the other side. This symptom lateralization is diagnostically important …
eventually spread to the other side. This symptom lateralization is diagnostically important …