Early developmental conditioning of later health and disease: physiology or pathophysiology?

MA Hanson, PD Gluckman - Physiological reviews, 2014 - journals.physiology.org
Extensive experimental animal studies and epidemiological observations have shown that
environmental influences during early development affect the risk of later pathophysiological …

Epigenetics across the human lifespan

RR Kanherkar, N Bhatia-Dey, AB Csoka - Frontiers in cell and …, 2014 - frontiersin.org
Epigenetics has the potential to explain various biological phenomena that have heretofore
defied complete explication. This review describes the various types of endogenous human …

Environmental epigenetics and a unified theory of the molecular aspects of evolution: a neo-Lamarckian concept that facilitates neo-Darwinian evolution

MK Skinner - Genome biology and evolution, 2015 - academic.oup.com
Environment has a critical role in the natural selection process for Darwinian evolution. The
primary molecular component currently considered for neo-Darwinian evolution involves …

Alterations in sperm DNA methylation, non-coding RNA and histone retention associate with DDT-induced epigenetic transgenerational inheritance of disease

MK Skinner, M Ben Maamar, I Sadler-Riggleman… - Epigenetics & …, 2018 - Springer
Background Environmental toxicants such as DDT have been shown to induce the
epigenetic transgenerational inheritance of disease (eg, obesity) through the germline. The …

Impact of Maternal Diet on the Epigenome during In Utero Life and the Developmental Programming of Diseases in Childhood and Adulthood

HS Lee - Nutrients, 2015 - mdpi.com
Exposure to environmental factors in early life can influence developmental processes and
long-term health in humans. Early life nutrition and maternal diet are well-known examples …

Transgenerational developmental programming

CE Aiken, SE Ozanne - Human reproduction update, 2014 - academic.oup.com
BACKGROUND The concept of developmental programming suggests that the early life
environment influences offspring characteristics in later life, including the propensity to …

[KNIHA][B] The rise of Homo sapiens: The evolution of modern thinking

FL Coolidge, TG Wynn - 2018 - books.google.com
The Rise of Homo sapiens provides an unrivalled interdisciplinary introduction to the subject
of hominin cognitive evolution that is appropriate for general audiences and students in …

Endocrine disruptor induction of epigenetic transgenerational inheritance of disease

MK Skinner - Molecular and cellular endocrinology, 2014 - Elsevier
Environmental exposures such as toxicants, nutrition and stress have been shown to
promote the epigenetic transgenerational inheritance of disease susceptibility. Endocrine …

The developmental origins of health and disease (DOHaD) concept: past, present, and future

PD Gluckman, T Buklijas, MA Hanson - The epigenome and developmental …, 2016 - Elsevier
The “developmental origins of health and disease”(DOHaD) is a concept that has emerged
over the past 50 years, linking the state of health and risk from disease in later childhood …

Pesticide methoxychlor promotes the epigenetic transgenerational inheritance of adult-onset disease through the female germline

M Manikkam, MM Haque, C Guerrero-Bosagna… - PloS one, 2014 - journals.plos.org
Environmental compounds including fungicides, plastics, pesticides, dioxin and
hydrocarbons can promote the epigenetic transgenerational inheritance of adult-onset …