Dopamine beta‐hydroxylase (DβH) is an essential neurotransmitter‐synthesizing enzyme
that catalyzes the formation of norepinephrine (NE) from dopamine and has been …

Introduction Despite a large number of commercially available drugs, hypertension and
related cardiovascular diseases remain a global problem. It is thus imperative that novel …

Fetal Alcohol Spectrum Disorder (FASD) is a common neurodevelopmental disorder that
affects an estimated 2–5% of North Americans. FASD is induced by prenatal alcohol …

Monitoring the concentration of norepinephrine (NE), epinephrine (Ep) and dopamine-β-
hydroxylase (DβH) is of great importance in studying and diagnosing related diseases. In …

Bioinformatics is an interconnected subject of science dealing with diverse fields including
biology, chemistry, physics, statistics, mathematics, and computer science as the key fields …

Abstract Background: Dopamine-β-hydroxylase (DBH, EC 1.14. 17.1), which converts
dopamine to norepinephrine, is a candidate gene in neuropsychiatric diseases. Aim: To …

Methods The dopamine and a computational model of the copper superoxo complex on
D\(\beta\) M were optimized at B3LYP-D3 (BJ)/6-311 G (d, p) level theory in the Gaussian 16 …

Genetic perturbations in dopamine neurotransmission and calcium signaling pathways are
implicated in the etiology of schizophrenia. We aimed to test the association of a functional …

Abstract Dopamine-β-hydroxylase (DBH, EC 1.14. 17.1) is an enzyme with implications in
various neuropsychiatric and cardiovascular diseases and is a known drug target. There is a …

The brain and the heart are arguably the two most important organs of the human body. It is
thus no surprise that diseases of the brain and heart are of the highest concern and are the …