Emerging biomarkers in thyroid practice and research

S Agarwal, A Bychkov, CK Jung - Cancers, 2021 - mdpi.com
Simple Summary Tumor biomarkers are molecules at genetic or protein level, or certain
evaluable characteristics. These help in perfecting patient management. Over the past …

[HTML][HTML] Prevalence of BRAFV600E mutation in Asian series of papillary thyroid carcinoma—a contemporary systematic review

FA Rashid, J Munkhdelger, J Fukuoka, A Bychkov - Gland Surgery, 2020 - ncbi.nlm.nih.gov
Papillary thyroid carcinoma (PTC), the most common malignancy of the endocrine system, is
frequently driven by BRAF V600E mutation, which was reported in 35–60% cases in …

PD-L1 expression and its modulating factors in anaplastic thyroid carcinoma: a multi-institutional study

S Agarwal, CK Jung, P Gaddam… - The American Journal …, 2024 - journals.lww.com
Anti-PD immunotherapy is currently under investigation in anaplastic thyroid carcinoma
(ATC). Tumor cell surface PD-L1 expression is considered predictive of therapeutic …

CD73 overexpression promotes progression and recurrence of papillary thyroid carcinoma

YM Jeong, H Cho, TM Kim, Y Kim, S Jeon, A Bychkov… - Cancers, 2020 - mdpi.com
Simple Summary This study aimed to evaluate the clinicopathologic significance of CD73
expression in patients with papillary thyroid carcinoma (PTC) and the potential for CD73 to …

[HTML][HTML] Molecular correlates and nuclear features of encapsulated follicular-patterned thyroid neoplasms

CK Jung, A Bychkov, DE Song, JH Kim… - Endocrinology and …, 2021 - synapse.koreamed.org
Background Assessing nuclear features is diagnostically challenging in the aspect of thyroid
pathology. The aim of this study was to determine whether pathologists could distinguish …

Paving the path toward multi-omics approaches in the diagnostic challenges faced in thyroid pathology

I Piga, V L'Imperio, G Capitoli, V Denti… - Expert Review of …, 2023 - Taylor & Francis
Introduction Despite advancements in diagnostic methods, the classification of
indeterminate thyroid nodules still poses diagnostic challenges not only in pre-surgical …

Comparative efficiency of differential diagnostic methods for the identification of BRAF V600E gene mutation in papillary thyroid cancer

Q Liu, X Jiang, W Tu, L Liu… - Experimental and …, 2024 - spandidos-publications.com
V‑Raf murine sarcoma viral oncogene homolog B1 (BRAF) encodes a serine‑threonine
kinase. The V600E point mutation in the BRAF gene is the most common mutation …

VE1 immunohistochemistry is an adjunct tool for detection of BRAFV600E mutation: Validation in thyroid cancer patients

FA Rashid, S Tabassum, MS Khan… - Journal of Clinical …, 2021 - Wiley Online Library
Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy among other
endocrine tumors, and BRAFV600E is a frequent genetic mutation occurring in the disease …

Prognostic Value of LINC-ROR (rs1942347) Variant in Patients with Colon Cancer Harboring BRAF Mutation: A Propensity Score-Matched Analysis

AAM Shaalan, SH Mokhtar, HT Ahmedah, AI Almars… - Biomolecules, 2022 - mdpi.com
Emerging studies show that long intergenic non-protein coding RNA, regulator of
reprogramming (LINC-ROR) is aberrantly expressed in several types of cancer, including …

Prognostic implications of CD10 and CD15 expression in papillary thyroid carcinoma

EJ Oh, A Bychkov, H Cho, TM Kim, JS Bae, DJ Lim… - Cancers, 2020 - mdpi.com
Patients with papillary thyroid carcinoma (PTC) have excellent survival, but recurrence
remains a major problem in the management of PTC. We aimed to determine the prognostic …