The Simpson grading scale, developed in 1957 by Donald Simpson, has been considered
the gold standard for defining the surgical extent of resection for WHO grade I meningiomas …

Meningioma is the most frequent primary tumor of the central nervous system. Important
advances have been achieved in the treatment of meningioma in recent decades. Although …

Abstract Treatment of the tumor and dural margin with surgery and sometimes radiation are
cornerstones of therapy for meningioma. Molecular classifications have provided insights …

Simple Summary Since the initial publication of the Simpson Grade scale, the management
paradigm for intracranial meningiomas has significantly evolved. The generalized …

OBJECTIVE Anterior skull base meningiomas are benign lesions that cause neurological
symptoms through mass effect on adjacent neurovascular structures. While traditional …

Meningiomas present as intracranial extra-axial lesions with dural attachment, which are
primarily managed surgically. The extent of resection (EOR) may vary depending on patient …

Purpose There is no evidence-based systemic therapy for patients with progressive
meningiomas for whom surgery or external radiotherapy is no longer an option. In this study …

OBJECTIVE Recently, the prognostic value of the Simpson resection grading scale has
been called into question for modern meningioma surgery. In this study, the authors …

Technological (and also methodological) advances in neurosurgery and neuroimaging have
prompted a reappraisal of Simpson's grading of the extent of meningioma resections. To the …

Background Mutations in the telomerase reverse transcriptase promoter (TERTp) region
have been associated with worse prognosis in some cancers. Meningiomas are the most …