Introduction: An increasing number of patients present with multiple symptoms affecting
many organs including the brain due to multiple mediators released by mast cells. These …

Introduction Mast cells are found in all tissues and express numerous surface receptors
allowing them to sense and respond to allergic, autoimmune, environmental …

Mast cell activation plays an important role in stress-mediated disease pathogenesis.
Chronic stress cause or exacerbate aging and age-dependent neurodegenerative diseases …

Objective Atopic diseases worsen with psychological stress, but how stress contributes to
their pathogenesis is still not clear. We review the evidence supporting the premise that …

This editorial focuses on recent progress reports on mast cells (MCs) and IL-1-family
cytokines in the dynamics of inflammation. MCs are cells of haematopoietic derivation that …

Brain microglia cells are responsible for recognizing foreign bodies and act by activating
other immune cells. Microglia react against infectious agents that cross the blood-brain …

The wound healing process is a multifaceted sequence of activities associated with tissue
restoration. Novel approaches for the perfection of wound healing have been determined as …

Tick serine protease inhibitors (serpins) play crucial roles in tick feeding and pathogen
transmission. We demonstrate that Ixodes scapularis (Ixs) nymph tick saliva serpin (S) 41 …

The liver is a major metabolic organ and an immunologically complex organ. It produces
and uses many substances such as acute phase proteins, cytokines, chemokines, and …

Mature dendritic cells (DCs) play a pathogenic role in atherosclerosis. Our previous study
demonstrated that exogenous interleukin (IL)-37 suppresses the maturation of DCs, induces …