New treatment strategies for advanced-stage gastrointestinal stromal tumours

LR Klug, HM Khosroyani, JD Kent… - Nature reviews Clinical …, 2022 - nature.com
When gastrointestinal stromal tumour (GIST), the most common form of sarcoma, was first
recognized as a distinct pathological entity in the 1990s, patients with advanced-stage …

Advances in immunology and immunotherapy for mesenchymal gastrointestinal cancers

B Li, H Chen, S Yang, F Chen, L Xu, Y Li, M Li, C Zhu… - Molecular cancer, 2023 - Springer
Mesenchymal gastrointestinal cancers are represented by the gastrointestinal stromal
tumors (GISTs) which occur throughout the whole gastrointestinal tract, and affect human …

[HTML][HTML] Soft tissue and visceral sarcomas: ESMO–EURACAN–GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up☆

A Gronchi, AB Miah, AP Dei Tos, N Abecassis… - Annals of …, 2021 - Elsevier
Highlights•This Clinical Practice Guideline provides key recommendations on the
management of soft tissue and visceral sarcomas.•Recommendations have been agreed …

Osteosarcoma: current concepts and evolutions in management principles

P Pilavaki, A Gahanbani Ardakani, P Gikas… - Journal of Clinical …, 2023 - mdpi.com
Osteosarcoma is a rare malignancy arising from mesenchymal tissue, and represents the
most common bone sarcoma. The management of osteosarcoma is challenging, and …

Updates in the diagnosis and management of small-bowel tumors

E Vlachou, A Koffas, C Toumpanakis… - Best Practice & Research …, 2023 - Elsevier
Small-bowel tumors represent a rare entity comprising 0.6% of all new cancer cases in the
US, and only 3% of all gastrointestinal neoplasms. They are a heterogenous group of …

Discontinuation versus continuation of imatinib in patients with advanced gastrointestinal stromal tumours (BFR14): exploratory long-term follow-up of an open-label …

JY Blay, Q Devin, F Duffaud, M Toulmonde… - The Lancet …, 2024 - thelancet.com
Background The long-term impact of tyrosine kinase inhibitor (TKI) discontinuation on
resistance and survival in patients with advanced gastrointestinal stromal tumours (GIST) is …

Novel therapeutic options for solitary fibrous tumor: antiangiogenic therapy and beyond

A de Bernardi, A Dufresne, F Mishellany, JY Blay… - Cancers, 2022 - mdpi.com
Simple Summary In the latest WHO classification, solitary fibrous tumors (SFTs) are now
subdivided into benign SFT (intermediate category (locally aggressive)), SFT NOS …

Deep learning predicts patients outcome and mutations from digitized histology slides in gastrointestinal stromal tumor

Y Fu, M Karanian, R Perret, A Camara… - Npj Precision …, 2023 - nature.com
Risk assessment of gastrointestinal stromal tumor (GIST) according to the AFIP/Miettinen
classification and mutational profiling are major tools for patient management. However, the …

EUS-Guided Diagnosis of Gastric Subepithelial Lesions, What Is New?

T Vasilakis, D Ziogas, G Tziatzios, P Gkolfakis… - Diagnostics, 2023 - mdpi.com
Gastric subepithelial lesions (SELs) are intramural lesions that arise underneath the gastric
mucosa. SELs can be benign, but can also be malignant or have malignant potential …

Incidence and survival outcomes of gastrointestinal stromal tumors

CS Alvarez, MB Piazuelo… - JAMA Network …, 2024 - jamanetwork.com
Importance The incidence of gastrointestinal stromal tumors (GISTs) increased after the
implementation of GIST-specific histology coding in 2001, but updated data on trends and …