When gastrointestinal stromal tumour (GIST), the most common form of sarcoma, was first
recognized as a distinct pathological entity in the 1990s, patients with advanced-stage …

Mesenchymal gastrointestinal cancers are represented by the gastrointestinal stromal
tumors (GISTs) which occur throughout the whole gastrointestinal tract, and affect human …

Highlights•This Clinical Practice Guideline provides key recommendations on the
management of soft tissue and visceral sarcomas.•Recommendations have been agreed …

Osteosarcoma is a rare malignancy arising from mesenchymal tissue, and represents the
most common bone sarcoma. The management of osteosarcoma is challenging, and …

Gastrointestinal stromal tumor (GIST) is the most common sarcoma located in
gastrointestinal tract and derived from the interstitial cell of Cajal (ICC) lineage. Both ICC …

Simple Summary In the latest WHO classification, solitary fibrous tumors (SFTs) are now
subdivided into benign SFT (intermediate category (locally aggressive)), SFT NOS …

Gastrointestinal stromal tumours (GISTs) are soft-tissue sarcomas of the gastrointestinal
tract. Surgery is the standard treatment for localised disease, but the risk of relapse and …

Background We investigated the impact of the implementation of a network of reference
centers for sarcomas (NETSARC) on the care and survival of sarcoma patients in France …

Avapritinib is the only potent and selective inhibitor approved for the treatment of D842V-
mutant gastrointestinal stromal tumors (GIST), the most common primary mutation of the …

Background The long-term impact of tyrosine kinase inhibitor (TKI) discontinuation on
resistance and survival in patients with advanced gastrointestinal stromal tumours (GIST) is …