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[HTML][HTML] Conjugated linoleic acid (CLA) as a functional food: Is it beneficial or not?
S Badawy, Y Liu, M Guo, Z Liu, C **e… - Food Research …, 2023 - Elsevier
Conjugated linoleic acid (CLA) has attracted great attention in recent years as a popular
class of functional food that is broadly used. It refers to a group of geometric and positional …
class of functional food that is broadly used. It refers to a group of geometric and positional …
[HTML][HTML] Molecular genetic contributions to social deprivation and household income in UK Biobank
Individuals with lower socio-economic status (SES) are at increased risk of physical and
mental illnesses and tend to die at an earlier age [1–3]. Explanations for the association …
mental illnesses and tend to die at an earlier age [1–3]. Explanations for the association …
Discovery of an Enzyme-Activated Fluorogenic Probe for In Vivo Profiling of Acylaminoacyl-Peptide Hydrolase
SY Liu, H Wang, YY Zhang, LY Huang - Analytical Chemistry, 2025 - ACS Publications
Acylaminoacyl-peptide hydrolase (APEH), a serine peptidase that belongs to the prolyl
oligopeptidase (POP) family, catalyzes removal of N-terminal acetylated amino acid …
oligopeptidase (POP) family, catalyzes removal of N-terminal acetylated amino acid …
A deeply conserved protease, acylamino acid-releasing enzyme (AARE), acts in ageing in Physcomitrella and Arabidopsis
Reactive oxygen species (ROS) are constant by-products of aerobic life. In excess, ROS
lead to cytotoxic protein aggregates, which are a hallmark of ageing in animals and linked to …
lead to cytotoxic protein aggregates, which are a hallmark of ageing in animals and linked to …
[HTML][HTML] Trans10, cis12-conjugated linoleic acid exhibits a stronger antioxidant capacity than cis9, trans11-conjugated linoleic acid in primary cultures of laying hen …
X Qi, J Wang, H Yue, S Wu, Y Zhang, H Ni, Y Guo… - Poultry Science, 2018 - Elsevier
The objective of this study consisting of 2 trials was to investigate the antioxidant role of
conjugated linoleic acid (CLA) isomers (c9, t11-CLA and t10, c12-CLA) and the underlying …
conjugated linoleic acid (CLA) isomers (c9, t11-CLA and t10, c12-CLA) and the underlying …
Impact of additives on thermally-induced trans isomers in 9c, 12c linoleic acid triacylglycerol
Q Guo, Y Ha, Q Li, J **, Z Deng, Y Li, S Zhang - Food Chemistry, 2015 - Elsevier
Trilinolein, with or without additives, was placed in glass ampoules and subjected to thermal
treatment at 180° C or 240° C for 8 h. Thermal treatment of trilinolein at 180° C and 240° C …
treatment at 180° C or 240° C for 8 h. Thermal treatment of trilinolein at 180° C and 240° C …
Low erythrocyte levels of proteasome and acyl-peptide hydrolase (APEH) activities in Alzheimer's disease: a sign of defective proteostasis?
Alzheimer's disease (AD) is a progressive, multifactorial neurodegenerative disorder that is
the main cause of dementia. To date, there are no definitive diagnostic tests that can predict …
the main cause of dementia. To date, there are no definitive diagnostic tests that can predict …
A bacterial acyl aminoacyl peptidase couples flexibility and stability as a result of cold adaptation
Life in cold environments requires an overall increase in the flexibility of macromolecular
and supramolecular structures to allow biological processes to take place at low …
and supramolecular structures to allow biological processes to take place at low …
A carbapenem antibiotic inhibiting a mammalian serine protease: structure of the acylaminoacyl peptidase–meropenem complex
The structure of porcine AAP (pAAP) in a covalently bound complex with meropenem was
determined by cryo-EM to 2.1 Å resolution, showing the mammalian serine-protease …
determined by cryo-EM to 2.1 Å resolution, showing the mammalian serine-protease …
[HTML][HTML] APEH inhibition affects osteosarcoma cell viability via downregulation of the proteasome
The proteasome is a multienzymatic complex that controls the half-life of the majority of
intracellular proteins, including those involved in apoptosis and cell-cycle progression …
intracellular proteins, including those involved in apoptosis and cell-cycle progression …