Hydrogenation is one of the most fundamental transformations in organic synthesis, and its
industrial applications span from fine chemicals to pharmaceuticals synthesis. 1− 3 Direct …

Deracemisation of racemic compounds is still the most important strategy to produce
optically pure compounds despite many recent advances in asymmetric synthesis …

The dynamic kinetic resolution of β-aryl α-keto esters has been accomplished using a newly
designed (arene) RuCl (monosulfonamide) transfer hydrogenation catalyst. This dynamic …

Pseudoephenamine is shown to be a versatile chiral auxiliary for asymmetric synthesis. It is
free from regulatory restrictions and exhibits remarkable stereocontrol in alkylation reactions …

Optically active amines represent critically important subunits in bioactive natural products
and pharmaceuticals, as well as key scaffolds in chiral catalysts and ligands. Kinetic …

A dynamic kinetic resolution of β-halo α-keto esters in an asymmetric homoenolate reaction
is described. A chiral N-hetereocyclic carbene catalyzes the a3→ d3-umpolung addition of …

Over the last few decades, the development of new and highly efficient synthetic methods to
obtain chiral compounds has become an increasingly important and challenging research …

A series of α-amino ketones were reduced using asymmetric transfer hydrogenation (ATH)
through a dynamic kinetic resolution (DKR). The protecting group was matched to the …

The dynamic kinetic resolution of α-keto esters via asymmetric transfer hydrogenation has
been developed as a technique for the highly stereoselective construction of structurally …

The development of an efficient synthetic route for an optically active ceramide compound (d-
erythro-CER [NDS]) is described. The route proceeds through asymmetric transfer …