There is a growing recognition of the importance of the commensal intestinal microbiota in
the development and later function of the central nervous system. Research using germ-free …

Autoimmune diseases are a range of diseases in which the immune response to self-
antigens results in damage or dysfunction of tissues. Autoimmune diseases can be systemic …

Although the effects of commensal bacteria on intestinal immune development seem to be
profound, it remains speculative whether the gut microbiota influences extraintestinal …

Autoimmune diseases are among the leading causes of death among young and middle-
aged women in the United States. Incidence rates vary among the autoimmune diseases …

Rheumatoid arthritis (RA) is the most common systemic autoimmune disease, affecting∼
1% of the adult population worldwide, with an estimated heritability of 60%. To identify …

Interleukin (IL)-2 plays a crucial role in the maintenance of natural immunologic self-
tolerance. Neutralization of circulating IL-2 by anti–IL-2 monoclonal antibody for a limited …

Flavonoids are natural polyphenolic compounds which are included in a panoply of drugs
and used to treat and/or manage human ailments such as metabolic, cardiovascular …

The balance between regulatory and effector functions is important for maintaining efficient
immune responses, while avoiding autoimmunity. The inflammatory skin disease psoriasis is …

Background & Aims: We aimed to discern the relative risk for several chronic inflammatory
conditions in patients with ulcerative colitis (UC) and Crohn's disease. Methods: We used …

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