Digestion of human milk fat in healthy infants
Lipid digestion is critical for infant development, and yet, the interconnection between lipid
digestion and the microbiota is largely understudied. This review focuses on digestion of the …
digestion and the microbiota is largely understudied. This review focuses on digestion of the …
Critical aspects involved in lipid dispersion and digestion: emphasis on in vitro models and factors influencing lipolysis of oral lipid based formulations
Understanding the mechanisms underlying the dispersion and digestion process is vital in
the development of oral lipid-based formulations (LBFs). In vitro lipolysis models mimic the …
the development of oral lipid-based formulations (LBFs). In vitro lipolysis models mimic the …
Lowering of cholesterol bioaccessibility and serum concentrations by saponins: in vitro and in vivo studies
Using an in vitro digestion model, we studied the effect of six saponin extracts on the
bioaccessibility of cholesterol and saturated fatty acids (SFAs). In the absence of saponins …
bioaccessibility of cholesterol and saturated fatty acids (SFAs). In the absence of saponins …
[HTML][HTML] The impact of oat structure and β-glucan on in vitro lipid digestion
MML Grundy, J Quint, A Rieder, S Ballance… - Journal of functional …, 2017 - Elsevier
Oat β-glucan has been shown to play a positive role in influencing lipid and cholesterol
metabolism. However, the mechanisms behind these beneficial effects are not fully …
metabolism. However, the mechanisms behind these beneficial effects are not fully …
[HTML][HTML] Usefulness of 1H NMR in assessing the extent of lipid digestion
Abstract Proton Nuclear Magnetic Resonance (1 H NMR) is proved to be, for the first time, a
very useful technique in monitoring the extent of lipid hydrolysis in digestion processes …
very useful technique in monitoring the extent of lipid hydrolysis in digestion processes …
[HTML][HTML] Mechanisms of dissolution and crystallization of amorphous glibenclamide
Amorphous solid dispersions enhance the dissolution and oral bioavailability of poorly water-
soluble drugs. However, the link between polymer properties and formulation performance …
soluble drugs. However, the link between polymer properties and formulation performance …
The mechanism of lowering cholesterol absorption by calcium studied by using an in vitro digestion model
Studies in humans show that a calcium-enriched diet leads to lower cholesterol in blood
serum. This phenomenon is usually explained in the literature with a reduced cholesterol …
serum. This phenomenon is usually explained in the literature with a reduced cholesterol …
[HTML][HTML] Cholesterol solubilization: Interplay between phytosterols, saponins and lipid digestion products
S Tsibranska-Gyoreva, V Petkov, V Katev… - Colloids and Surfaces A …, 2023 - Elsevier
High plasma concentrations of cholesterol are associated with cardio-vascular disease
complications and high risk of myocardial infarction. The absorption of dietary cholesterol …
complications and high risk of myocardial infarction. The absorption of dietary cholesterol …
Molecular dynamics simulation of the aggregation patterns in aqueous solutions of bile salts at physiological conditions
Classical molecular dynamics simulations are employed to monitor the aggregation
behavior of six bile salts (nonconjugated and glycine-and taurine-conjugated sodium …
behavior of six bile salts (nonconjugated and glycine-and taurine-conjugated sodium …
Self-assembled structures formed during lipid digestion: characterization and implications for oral lipid-based drug delivery systems
There is increasing interest in the use of lipid-based formulations for the delivery of poorly
water-soluble drugs. After ingestion of the formulation, exposure to the gastrointestinal …
water-soluble drugs. After ingestion of the formulation, exposure to the gastrointestinal …