Metal complexes with Schiff bases: Data collection and recent studies on biological activities

MS Sinicropi, J Ceramella, D Iacopetta… - International Journal of …, 2022 - mdpi.com
Metal complexes play a crucial role in pharmaceutical sciences owing to their wide and
significant activities. Schiff bases (SBs) are multifaceted pharmacophores capable of forming …

Transition Metal Complexes as Therapeutics: A New Frontier in Combatting Neurodegenerative Disorders through Protein Aggregation Modulation

GR Navale, I Ahmed, MH Lim… - Advanced Healthcare …, 2024 - Wiley Online Library
Neurodegenerative disorders (NDDs) are a class of debilitating diseases that progressively
impair the protein structure and result in neurological dysfunction in the nervous system …

Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular docking studies of new imidazolyl hydrazone derivatives

M Tapera, H Kekeçmuhammed, B Tüzün… - Journal of molecular …, 2022 - Elsevier
A new series of imidazolyl hydrazone derivatives IA (1-12) were prepared from a
condensation reaction between indoline-2, 3-dione (isatin) and 2 …

Improvement of photochemical and enzyme inhibition properties of new BODIPY compound by conjugation with cisplatin

CC Karanlık, G Karanlık, P Taslimi, A Erdoğmuş - Polyhedron, 2022 - Elsevier
In this study, new BODIPY complexes were synthesized, characterized and investigated for
their some metabolic enzyme inhibition and photophysicochemical properties. BODIPY …

In vitro cytotoxic effects, in silico studies, some metabolic enzymes inhibition, and vibrational spectral analysis of novel β-amino alcohol compounds

A Tas, B Tüzün, AN Khalilov, P Taslimi… - Journal of Molecular …, 2023 - Elsevier
In this study, an efficient single-step method for the preparation of β-amino alcohols (1–3) in
aqueous media was applied. The aim was to investigate the cytotoxic activity of Compounds …

The Evaluation of Anticancer, Antioxidant, Antidiabetic and Anticholinergic Potentials of Endemic Rhabdosciadium microcalycinum Supported by Molecular Docking …

MK Erdogan, R Gundogdu, Y Yapar… - …, 2022 - Wiley Online Library
Lung cancer is the most common cancer worldwide and the leading cause of cancer‐related
death. Plant‐derived natural products and compounds are an inspiring source of …

Quinoline‐fused both non‐peripheral and peripheral ZnII and MgII phthalocyanines: Anti‐cholinesterase, anti‐α‐glucosidase, DNA nuclease, antioxidant activities …

H Yalazan, B Tüzün, D Akkaya, B Barut… - Applied …, 2022 - Wiley Online Library
Quinoline‐fused ZnII (ZnPcp/ZnPcnp) and MgII (MgPcp/MgPcnp) phthalocyanines with four
4‐methylquinolin‐2‐ol (1) at non‐peripheral or peripheral positions of the phthalocyanine …

Beyond the classical amyloid hypothesis in Alzheimer's disease: Molecular insights into current concepts of pathogenesis, therapeutic targets, and study models

A Theerasri, S Janpaijit, T Tencomnao… - WIREs Mechanisms …, 2023 - Wiley Online Library
Alzheimer's disease (AD) is one of the progressive neurodegenerative disorders and the
most common cause of dementia in the elderly worldwide causing difficulties in the daily life …

Therapy and diagnosis of Alzheimer's disease: from discrete metal complexes to metal–organic frameworks

A García-García, S Rojas… - Journal of Materials …, 2023 - pubs.rsc.org
Alzheimer's disease (AD) is a neurodegenerative disorder affecting 44 million people
worldwide. Although many issues (pathogenesis, genetics, clinical features, and …

Synthesis, characterization, crystal structure, molecular docking, and biological studies of Cu, Ni and Co metal complexes of pyrazole

I Mahmudov, B Ibrahimova, P Taslimi… - Journal of Molecular …, 2024 - Elsevier
Utilizing ligands based on pyrazole synthesized some transition metal complexes. Selected
salts such as Co (CH 3 COO) 2· 4H 2 O, Ni (CH 3 COO) 2· 4H 2 O (in the presence of …