Heme, an iron-containing porphyrin, is of vital importance for cells due to its involvement in
several biological processes, including oxygen transport, energy production and drug …

Heme is an iron-containing prosthetic group necessary for the function of several proteins
termed" hemoproteins." Erythrocytes contain most of the body's heme in the form of …

Heme is required for cell respiration and survival. Nevertheless, its intracellular levels need
to be finely regulated to avoid heme excess, which may catalyze the production of reactive …

Congenital insensitivity to pain (CIP) and hereditary sensory and autonomic neuropathies
(HSAN) are clinically and genetically heterogeneous disorders exclusively or predominantly …

Heme (iron-protoporphyrin IX) is an essential co-factor involved in several biological
processes, including neuronal survival and differentiation. Nevertheless, an excess of free …

The Irish national registry for inherited retinal degenerations (Target 5000) is a clinical and
scientific program to identify individuals in Ireland with inherited retinal disorders and to …

Abstract The Feline Leukemia Virus Subgroup C Receptor 1a (FLVCR1a) is a member of the
SLC49 Major Facilitator Superfamily of transporters. Initially recognized as the receptor for …

Mitochondrial dysfunction has achieved an increasing interest in the field of
neurodegeneration as a pathological hallmark for different disorders. The impact of …

The mutations of the feline leukemia virus subgroup C receptor‐related protein 1 (FLVCR1)
cause ataxia with retinitis pigmentosa. Recent studies indicated a large variation in the …

Retinitis pigmentosa (RP) is an inherited retinal dystrophy caused by the loss of
photoreceptors and retinal pigment epithelial atrophy, leading to severe visual impairment or …