A brief overview is given of platinum anticancer drugs in routine clinical use and under
clinical development worldwide. Details of the binding of these drugs with nucleic acids, the …

Metal coordination compounds with 'slow'metal-ligand exchange rates, comparable to those
of cell division processes, often appear to be highly active in killing cancer cell lines. This is …

Platinum-based anticancer chemotherapy constitutes a cornerstone for the treatment of
various solid tumors. However, existing platinum drugs like cisplatin encounter many …

Phenanthroline derivatives are of interest due to their potential activity against cancer, and
viral, bacterial, and fungal infections. In a search for highly specific antitumor and …

Platinum diam (m) ine complexes, such as cisplatin, are successful anticancer drugs, but
suffer from problems of resistance and side‐effects. Photoactivatable PtIV prodrugs offer the …

The study of the reactivity of three 1-(2-dimethylaminoethyl)-1H-pyrazole derivatives of
general formula [1-(CH2) 2NMe2}-3, 5-R2-pzol]{where pzol represents pyrazole and RH …

The book provides a detailed state-of-the-art overview of inorganic chemistry applied to
medicinal chemistry and biology. It covers the newly emerging field of metals in medicine …

Cytostatic agents that interfere with specific cellular components to prevent cancer cell
growth offer an attractive alternative, or complement, to traditional cytotoxic chemotherapy …

A series of gold (I) and platinum (II) complexes of the type [Au (SR)(P)] and trans-[Pt (SR) 2
(P) 2][SR= 2-thiopyridine (SPy), 2-thiopyrimidine (SPyrim); P= 1, 3, 5-triaza-7 …

A series of ternary metal (II) complexes {M (phen)(edda); 1a (Cu), 1b (Co), 1c (Zn), 1d (Ni);
H2edda= N, N′-ethylenediaminediacetic acid} of N, N′-ethylene-bridged diglycine and 1 …