Adaptive proton therapy

H Paganetti, P Botas, GC Sharp… - Physics in Medicine & …, 2021 - iopscience.iop.org
Radiation therapy treatments are typically planned based on a single image set, assuming
that the patient's anatomy and its position relative to the delivery system remains constant …

Proton versus photon radiation therapy: A clinical review

Z Chen, MM Dominello, MC Joiner… - Frontiers in …, 2023 - frontiersin.org
While proton radiation therapy offers substantially better dose distribution characteristics
than photon radiation therapy in certain clinical applications, data demonstrating a …

Considerations for upright particle therapy patient positioning and associated image guidance

L Volz, Y Sheng, M Durante, C Graeff - Frontiers in Oncology, 2022 - frontiersin.org
Particle therapy is a rapidly growing field in cancer therapy. Worldwide, over 100 centers are
in operation, and more are currently in construction phase. The interest in particle therapy is …

Dual-and multi-energy CT for particle stop**-power estimation: current state, challenges and potential

M Yang, P Wohlfahrt, C Shen… - Physics in Medicine & …, 2023 - iopscience.iop.org
Range uncertainty has been a key factor preventing particle radiotherapy from reaching its
full physical potential. One of the main contributing sources is the uncertainty in estimating …

Image-guided proton therapy: A comprehensive review

SA Lane, JM Slater, GY Yang - Cancers, 2023 - mdpi.com
Simple Summary In proton therapy, there is a sharp peak in the delivered dose followed by a
rapid falloff, known as the Bragg peak, which is not present in photons. This allows for …

A high-granularity digital tracking calorimeter optimized for proton CT

J Alme, GG Barnaföldi, R Barthel, V Borshchov… - Frontiers in …, 2020 - frontiersin.org
A typical proton CT (pCT) detector comprises a tracking system, used to measure the proton
position before and after the imaged object, and an energy/range detector to measure the …

Status and innovations in pre-treatment CT imaging for proton therapy

P Wohlfahrt, C Richter - The British journal of radiology, 2020 - academic.oup.com
Pre-treatment CT imaging is a topic of growing importance in particle therapy. Improvements
in the accuracy of stop**-power prediction are demanded to allow for a dose conformality …

Meeting the detector challenges for pre-clinical proton and ion computed tomography

RP Johnson - Physics in Medicine & Biology, 2024 - iopscience.iop.org
Six decades after its conception, proton computed tomography (pCT) and proton
radiography have yet to be used in medical clinics. However, good progress has been made …

Latest developments in in-vivo imaging for proton therapy

K Parodi - The British journal of radiology, 2020 - academic.oup.com
Owing to the favorable physical and biological properties of swift ions in matter, their
application to radiation therapy for highly selective cancer treatment is rapidly spreading …

Range uncertainty reductions in proton therapy may lead to the feasibility of novel beam arrangements which improve organ‐at‐risk sparing

S Tattenberg, TM Madden, T Bortfeld, K Parodi… - Medical …, 2022 - Wiley Online Library
Purpose In proton therapy, dose distributions are currently often conformed to organs at risk
(OARs) using the less sharp dose fall‐off at the lateral beam edge to reduce the effects of …