Prenatal poly (i: C) exposure and other developmental immune activation models in rodent systems
U Meyer - Biological psychiatry, 2014 - Elsevier
It is increasingly appreciated that altered neuroimmune mechanisms might play a role in the
development of schizophrenia and related psychotic illnesses. On the basis of human …
development of schizophrenia and related psychotic illnesses. On the basis of human …
Environmental risk factors for schizophrenia and bipolar disorder and their relationship to genetic risk: current knowledge and future directions
Schizophrenia (SZ) and bipolar disorder (BD) are severe psychiatric disorders which result
from complex interplay between genetic and environmental factors. It is well-established that …
from complex interplay between genetic and environmental factors. It is well-established that …
Brain volume in first-episode schizophrenia: systematic review and meta-analysis of magnetic resonance imaging studies
RG Steen, C Mull, R Mcclure, RM Hamer… - The British Journal of …, 2006 - cambridge.org
BackgroundStudies of people with schizophrenia assessed using magnetic resonance
imaging (MRI) usually include patients with first-episode and chronic disease, yet brain …
imaging (MRI) usually include patients with first-episode and chronic disease, yet brain …
The immune system and developmental programming of brain and behavior
The brain, endocrine, and immune systems are inextricably linked. Immune molecules have
a powerful impact on neuroendocrine function, including hormone–behavior interactions …
a powerful impact on neuroendocrine function, including hormone–behavior interactions …
Early-life programming of later-life brain and behavior: a critical role for the immune system
The immune system is well characterized for its critical role in host defense. Far beyond this
limited role however, there is mounting evidence for the vital role the immune system plays …
limited role however, there is mounting evidence for the vital role the immune system plays …
Stress in puberty unmasks latent neuropathological consequences of prenatal immune activation in mice
Prenatal infection and exposure to traumatizing experiences during peripuberty have each
been associated with increased risk for neuropsychiatric disorders. Evidence is lacking for …
been associated with increased risk for neuropsychiatric disorders. Evidence is lacking for …
A two-hit model of autism: Adolescence as the second hit
Adolescence brings dramatic changes in behavior and neural organization. Unfortunately,
for some 30% of individuals with autism, there is marked decline in adaptive functioning …
for some 30% of individuals with autism, there is marked decline in adaptive functioning …
Functional and evolutionary insights into human brain development through global transcriptome analysis
Our understanding of the evolution, formation, and pathological disruption of human brain
circuits is impeded by a lack of comprehensive data on the develo** brain transcriptome …
circuits is impeded by a lack of comprehensive data on the develo** brain transcriptome …
Virtual histology of cortical thickness and shared neurobiology in 6 psychiatric disorders
Importance Large-scale neuroimaging studies have revealed group differences in cortical
thickness across many psychiatric disorders. The underlying neurobiology behind these …
thickness across many psychiatric disorders. The underlying neurobiology behind these …
[HTML][HTML] The dual hit hypothesis of schizophrenia: Evidence from animal models
Schizophrenia is a heterogeneous psychiatric disorder, which can severely impact social
and professional functioning. Epidemiological and clinical studies show that schizophrenia …
and professional functioning. Epidemiological and clinical studies show that schizophrenia …