Schizophrenia (SZ) and bipolar disorder (BD) are severe psychiatric disorders which result
from complex interplay between genetic and environmental factors. It is well-established that …

It is increasingly appreciated that altered neuroimmune mechanisms might play a role in the
development of schizophrenia and related psychotic illnesses. On the basis of human …

Importance Large-scale neuroimaging studies have revealed group differences in cortical
thickness across many psychiatric disorders. The underlying neurobiology behind these …

The brain, endocrine, and immune systems are inextricably linked. Immune molecules have
a powerful impact on neuroendocrine function, including hormone–behavior interactions …

Adolescence brings dramatic changes in behavior and neural organization. Unfortunately,
for some 30% of individuals with autism, there is marked decline in adaptive functioning …

Prenatal infection and exposure to traumatizing experiences during peripuberty have each
been associated with increased risk for neuropsychiatric disorders. Evidence is lacking for …

Early life stress (ELS), in the form of childhood maltreatment, abuse, or neglect, increases
the risk for psychiatric sequelae later in life. The neurobiology of response to early stress …

Schizophrenia is a heterogeneous psychiatric disorder, which can severely impact social
and professional functioning. Epidemiological and clinical studies show that schizophrenia …

The immune system is well characterized for its critical role in host defense. Far beyond this
limited role however, there is mounting evidence for the vital role the immune system plays …

Accumulating evidence supports the view that deregulation of the immune system
represents an important vulnerability factor for psychosis. In a subgroup of psychotic …