[HTML][HTML] Long noncoding RNAs as promising biomarkers in cancer

O Beylerli, I Gareev, A Sufianov, T Ilyasova… - Non-coding RNA …, 2022 - Elsevier
Despite many advances in diagnosis and therapy (surgery, radiation therapy,
chemotherapy), cancer remains one of the most important public health problems …

Cytoplasmic functions of long noncoding RNAs

JH Noh, KM Kim, WG McClusky… - Wiley …, 2018 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found
throughout the cell that lack protein‐coding function. Their functions are closely linked to …

Predicting the potential human lncRNA–miRNA interactions based on graph convolution network with conditional random field

W Wang, L Zhang, J Sun, Q Zhao… - Briefings in …, 2022 - academic.oup.com
Long non-coding RNA (lncRNA) and microRNA (miRNA) are two typical types of non-coding
RNAs (ncRNAs), their interaction plays an important regulatory role in many biological …

Using network distance analysis to predict lncRNA–miRNA interactions

L Zhang, P Yang, H Feng, Q Zhao, H Liu - … sciences: computational life …, 2021 - Springer
LncRNA–miRNA interactions contribute to the regulation of therapeutic targets and
diagnostic biomarkers in multifarious human diseases. However, it remains difficult to …

EIF4A3-induced circular RNA MMP9 (circMMP9) acts as a sponge of miR-124 and promotes glioblastoma multiforme cell tumorigenesis

R Wang, S Zhang, X Chen, N Li, J Li, R Jia, Y Pan… - Molecular cancer, 2018 - Springer
Abstract Background Circular RNAs (circRNAs) have been found to play critical roles in the
development and progression of various cancers. However, little is known about the effects …

LncRNA KLF3-AS1 in human mesenchymal stem cell-derived exosomes ameliorates pyroptosis of cardiomyocytes and myocardial infarction through miR-138-5p …

Q Mao, XL Liang, CL Zhang, YH Pang… - Stem cell research & …, 2019 - Springer
Aim Myocardial infarction (MI) is a severe disease with increased mortality and disability
rates, posing heavy economic burden for society. Exosomes were uncovered to mediate …

LncRNA HOXA-AS2 and its molecular mechanisms in human cancer

J Wang, Z Su, S Lu, W Fu, Z Liu, X Jiang, S Tai - Clinica chimica acta, 2018 - Elsevier
Long non-coding RNAs (lncRNAs), a novel class of noncoding RNAs, are commonly defined
as RNA molecules more than 200 nucleotides in length. Emerging research indicated that …

Unraveling the ncRNA landscape that governs colorectal cancer: a roadmap to personalized therapeutics

NM Hamdy, MB Zaki, NI Rizk, NM Abdelmaksoud… - Life Sciences, 2024 - Elsevier
Colorectal cancer (CRC) being one of the most common malignancies, has a significant
death rate, especially when detected at an advanced stage. In most cases, the fundamental …

The critical role of epigenetics in systemic lupus erythematosus and autoimmunity

H Long, H Yin, L Wang, ME Gershwin, Q Lu - Journal of autoimmunity, 2016 - Elsevier
One of the major disappointments in human autoimmunity has been the relative failure on
genome-wide association studies to provide “smoking genetic guns” that would explain the …

Exosome derived from tumor-associated macrophages: biogenesis, functions, and therapeutic implications in human cancers

M Zhou, X He, C Mei, C Ou - Biomarker Research, 2023 - Springer
Abstract Tumor-associated macrophages (TAMs), one of the most abundant immune cell
types in the tumor microenvironment (TME), account for approximately 50% of the local …