Amplifying “eat me signal” by immunogenic cell death for potentiating cancer immunotherapy

Y **, L Chen, J Tang, B Yu, W Shen… - Immunological …, 2024 - Wiley Online Library
Immunogenic cell death (ICD) is a unique mode of cell death, which can release
immunogenic damage‐associated molecular patterns (DAMPs) and tumor‐associated …

The triangular relationship between traditional Chinese medicines, intestinal flora, and colorectal cancer

Y Zou, S Wang, H Zhang, Y Gu, H Chen… - Medicinal Research …, 2024 - Wiley Online Library
Over the past decade, colorectal cancer has reported a higher incidence in younger adults
and a lower mortality rate. Recently, the influence of the intestinal flora in the initiation …

HMGB1 in the interplay between autophagy and apoptosis in cancer

R Chen, J Zou, X Zhong, J Li, R Kang, D Tang - Cancer Letters, 2024 - Elsevier
Lysosome-mediated autophagy and caspase-dependent apoptosis are dynamic processes
that maintain cellular homeostasis, ensuring cell health and functionality. The intricate …

Three‐in‐One Peptide Prodrug with Targeting, Assembly and Release Properties for Overcoming Bacterium‐Induced Drug Resistance and Potentiating Anti‐Cancer …

G Gao, YW Jiang, J Chen, X Xu, X Sun, H Xu… - Advanced …, 2024 - Wiley Online Library
The presence of bacteria in tumor results in chemotherapeutic drug resistance and weakens
the immune response in colorectal cancer. To overcome bacterium‐induced …

Metal coordination micelles for anti-cancer treatment by gene-editing and phototherapy

C Zhang, X Wang, G Liu, H Ren, J Li, Z Jiang… - Journal of Controlled …, 2023 - Elsevier
CRISPR-Cas9 is a central focus of the emerging field of gene editing and photodynamic
therapy (PDT) is a clinical-stage ablation modality combining photosensitizers with light …

Immunogenic cell death inducers for cancer therapy: an emerging focus on natural products

LL Zhang, DJ Zhang, JX Shi, MY Huang, JM Yu… - Phytomedicine, 2024 - Elsevier
Background Immunogenic cell death (ICD) is a specific form of regulated cell death induced
by a variety of stressors. During ICD, the dying cancer cells release damage-associated …

Efficient tumor synergistic chemoimmunotherapy by self-augmented ROS-responsive immunomodulatory polymeric nanodrug

J Song, M Cheng, Y **e, K Li, X Zang - Journal of nanobiotechnology, 2023 - Springer
Immunotherapy has emerged as a promising therapeutic strategy for cancer therapy.
However, the therapeutic efficacy has been distracted due to poor immunogenicity and …

The future of cancer vaccines against colorectal cancer

W Jia, X Shen, Z Guo, X Cheng… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Colorectal cancer (CRC) is the second most lethal malignancy worldwide.
Immune checkpoint inhibitors (ICIs) benefit only 15% of patients with mismatch repair …

Recent developments in chemodrug-loaded nanomedicines and their application in combination cancer immunotherapy

N Shim, H Cho, SI Jeon, K Kim - Journal of Pharmaceutical Investigation, 2024 - Springer
Background In recent studies of cancer therapies, chemodrugs have attracted interest,
acting not only as traditional chemotherapeutic agents but also as anticancer immune …

Strategies to enhance the therapeutic efficacy of anti-PD-1 antibody, anti-PD-L1 antibody and anti-CTLA-4 antibody in cancer therapy

X Su, J Li, X Xu, Y Ye, C Wang, G Pang, W Liu… - Journal of Translational …, 2024 - Springer
Although immune checkpoint inhibitors (anti-PD-1 antibody, anti-PD-L1 antibody, and anti-
CTLA-4 antibody) have displayed considerable success in the treatment of malignant …