Neuronal regulation of immunity: why, how and where?
M Schiller, TL Ben-Shaanan, A Rolls - Nature Reviews Immunology, 2021 - nature.com
Neuroimmunology is one of the fastest-growing fields in the life sciences, and for good
reason; it fills the gap between two principal systems of the organism, the nervous system …
reason; it fills the gap between two principal systems of the organism, the nervous system …
The HPA–immune axis and the immunomodulatory actions of glucocorticoids in the brain
MA Bellavance, S Rivest - Frontiers in immunology, 2014 - frontiersin.org
In response to physiological and psychogenic stressors, the hypothalamic–pituitary–adrenal
(HPA) axis orchestrates the systemic release of glucocorticoids (GCs). By virtue of nearly …
(HPA) axis orchestrates the systemic release of glucocorticoids (GCs). By virtue of nearly …
Repeated social defeat, neuroinflammation, and behavior: monocytes carry the signal
Mounting evidence indicates that proinflammatory signaling in the brain affects mood,
cognition, and behavior and is linked with the etiology of psychiatric disorders, including …
cognition, and behavior and is linked with the etiology of psychiatric disorders, including …
An inflammatory review of glucocorticoid actions in the CNS
SF Sorrells, RM Sapolsky - Brain, behavior, and immunity, 2007 - Elsevier
In recent years, the classic view that glucocorticoids, the adrenal steroids secreted during
stress, are universally anti-inflammatory has been challenged at a variety of levels. It was …
stress, are universally anti-inflammatory has been challenged at a variety of levels. It was …
Circadian regulation of depression: A role for serotonin
RA Daut, LK Fonken - Frontiers in neuroendocrinology, 2019 - Elsevier
Synchronizing circadian (24 h) rhythms in physiology and behavior with the environmental
light-dark cycle is critical for maintaining optimal health. Dysregulation of the circadian …
light-dark cycle is critical for maintaining optimal health. Dysregulation of the circadian …
Chronic stress and A lzheimer's disease: the interplay between the hypothalamic–pituitary–adrenal axis, genetics and microglia
Chronic psychosocial stress is increasingly being recognised as a risk factor for sporadic
Alzheimer's disease (AD). The hypothalamic–pituitary–adrenal axis (HPA axis) is the major …
Alzheimer's disease (AD). The hypothalamic–pituitary–adrenal axis (HPA axis) is the major …
Interleukin-1 (IL-1): a central regulator of stress responses
Ample evidence demonstrates that the pro-inflammatory cytokine interleukin-1 (IL-1),
produced following exposure to immunological and psychological challenges, plays an …
produced following exposure to immunological and psychological challenges, plays an …
Catecholamines mediate stress-induced increases in peripheral and central inflammatory cytokines
Proinflammatory cytokines act at receptors in the CNS to alter physiological and behavioral
responses. Exposure to stressors increases both peripheral and central proinflammatory …
responses. Exposure to stressors increases both peripheral and central proinflammatory …
Microglia inflammatory responses are controlled by an intrinsic circadian clock
The circadian system regulates many physiological functions including inflammatory
responses. For example, mortality caused by lipopolysaccharide (LPS) injection varies …
responses. For example, mortality caused by lipopolysaccharide (LPS) injection varies …
Regulatory and mechanistic actions of glucocorticoids on T and inflammatory cells
AC Liberman, ML Budziñski, C Sokn… - Frontiers in …, 2018 - frontiersin.org
Glucocorticoids (GCs) play an important role in regulating the inflammatory and immune
response and have been used since decades to treat various inflammatory and autoimmune …
response and have been used since decades to treat various inflammatory and autoimmune …