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Extending the potency and lifespan of antibiotics: inhibitors of gram-negative bacterial efflux pumps
M Duffey, RP Jumde, RMA da Costa… - ACS Infectious …, 2024 - ACS Publications
Efflux is a natural process found in all prokaryotic and eukaryotic cells that removes a
diverse range of substrates from inside to outside. Many antibiotics are substrates of …
diverse range of substrates from inside to outside. Many antibiotics are substrates of …
[PDF][PDF] Design, synthesis and bioactivity studies of novel triazolopyrimidinone compounds
This study was aimed to develop novel compounds to combat antimicrobial resistance,
which is one of the biggest threats to global health. For this purpose, compounds bearing …
which is one of the biggest threats to global health. For this purpose, compounds bearing …