Why is COVID-19 less severe in children? A review of the proposed mechanisms underlying the age-related difference in severity of SARS-CoV-2 infections

P Zimmermann, N Curtis - Archives of disease in childhood, 2021 - adc.bmj.com
In contrast to other respiratory viruses, children have less severe symptoms when infected
with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this …

Gut and airway microbiota dysbiosis and their role in COVID-19 and long-COVID

G Ancona, L Alagna, C Alteri, E Palomba… - Frontiers in …, 2023 - frontiersin.org
The gut microbiota plays a crucial role in human health and disease. Gut dysbiosis is known
to be associated with increased susceptibility to respiratory diseases and modifications in …

Microbiota modulation of the gut-lung axis in COVID-19

GLV de Oliveira, CNS Oliveira, CF Pinzan… - Frontiers in …, 2021 - frontiersin.org
COVID-19 is an infectious disease caused by the Severe Acute Respiratory Syndrome
Coronavirus-2 (SARS-CoV-2), and according to the World Health Organization (WHO), to …

Metagenomic analysis reveals oropharyngeal microbiota alterations in patients with COVID-19

S Ma, F Zhang, F Zhou, H Li, W Ge, R Gan… - … and Targeted Therapy, 2021 - nature.com
COVID-19 remains a serious emerging global health problem, and little is known about the
role of oropharynx commensal microbes in infection susceptibility and severity. Here, we …

The human microbiome and COVID-19: A systematic review

S Yamamoto, M Saito, A Tamura, D Prawisuda… - PloS one, 2021 - journals.plos.org
Background Human microbiotas are communities of microorganisms living in symbiosis with
humans. They play an important role in the host immune response to respiratory viral …

Microbiota and immunity during respiratory infections: lung and gut affair

V Marrella, F Nicchiotti, B Cassani - International journal of molecular …, 2024 - mdpi.com
Bacterial and viral respiratory tract infections are the most common infectious diseases,
leading to worldwide morbidity and mortality. In the past 10 years, the importance of lung …

A diagnostic host response biosignature for COVID-19 from RNA profiling of nasal swabs and blood

DL Ng, AC Granados, YA Santos, V Servellita… - Science …, 2021 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus
disease-19 (COVID-19), has emerged as the cause of a global pandemic. We used RNA …

[HTML][HTML] Nasal microbiota, olfactory health, neurological disorders and aging—A review

S Thangaleela, BS Sivamaruthi, P Kesika, M Bharathi… - Microorganisms, 2022 - mdpi.com
The nasal region is one of the distinct environments for the survival of various microbiota.
The human microbial niche begins to inhabit the human body right from birth, and the …

The nasopharyngeal microbiome in COVID-19

S Candel, SD Tyrkalska… - Emerging Microbes & …, 2023 - Taylor & Francis
The development of novel culture-independent techniques of microbial identification has
allowed a rapid progress in the knowledge of the nasopharyngeal microbiota and its role in …

SARS-CoV-2 infection and viral load are associated with the upper respiratory tract microbiome

C Rosas-Salazar, KS Kimura, MH Shilts… - Journal of Allergy and …, 2021 - Elsevier
Background Little is known about the relationships between severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), the respiratory virus responsible for the ongoing …