Summary Each year, the American Heart Association (AHA), in conjunction with the National
Institutes of Health and other government agencies, brings together in a single document the …

Summary Each year, the American Heart Association (AHA), in conjunction with the Centers
for Disease Control and Prevention, the National Institutes of Health, and other government …

Statins reduce cholesterol, prevent cardiovascular disease, and are among the most
commonly prescribed medications in the world. Statin‐associated musculoskeletal …

Metabolic diseases are the most common and rapidly growing health issues worldwide. The
massive population-based human genetics is crucial for the precise prevention and …

Despite scientific and clinical advances in the field of pharmacogenomics (PGx), application
into routine care remains limited. Opportunely, several implementation studies and …

Simvastatin is among the most commonly used prescription medications for cholesterol
reduction. A single coding single‐nucleotide polymorphism, rs4149056T> C, in SLCO1B1 …

Although the field of pharmacogenetics has existed for decades, practioners have been slow
to implement pharmacogenetic testing in clinical care. Numerous publications describe the …

Importance Whole-genome sequencing (WGS) is increasingly applied in clinical medicine
and is expected to uncover clinically significant findings regardless of sequencing indication …

Abstract The Clinical Pharmacogenetics Implementation Consortium (CPIC) publishes
genotype-based drug guidelines to help clinicians understand how available genetic test …

Both the Clinical Pharmacogenetics Implementation Consortium (CPIC) and Dutch
Pharmacogenetics Working Group provide therapeutic recommendations for well‐known …