[HTML][HTML] Current role of carbamazepine and oxcarbazepine in the management of epilepsy

A Beydoun, S DuPont, D Zhou, M Matta, V Nagire… - Seizure, 2020‏ - Elsevier
Epilepsy is one of the most common neurological disorders, affecting approximately 50
million people worldwide. Despite a dramatic increase in treatment options over the past 30 …

An updated overview on therapeutic drug monitoring of recent antiepileptic drugs

S Jacob, AB Nair - Drugs in R&D, 2016‏ - Springer
Given the distinctive characteristics of both epilepsy and antiepileptic drugs (AEDs),
therapeutic drug monitoring (TDM) can make a significant contribution to the field of …

[HTML][HTML] Review on the relevance of therapeutic drug monitoring of levetiracetam

J Sourbron, HY Chan, EA Wammes-van der Heijden… - Seizure, 2018‏ - Elsevier
Abstract Therapeutic Drug Monitoring (TDM) of anti-epileptic drugs (AEDs) is not routinely
performed, although this can guide the dosage regimen to achieve greater efficacy and …

Levetiracetam, lamotrigine and carbamazepine: which monotherapy during pregnancy?

L Mari, F Placidi, A Romigi, M Tombini… - Neurological …, 2022‏ - Springer
Objective Epilepsy treatment during pregnancy is still challenging. The study is aimed at
comparing the efficacy and safety of carbamazepine (CBZ), lamotrigine (LTG) and …

Seizure control and adverse outcomes of lamotrigine use during pregnancy: A systematic review and meta-analysis

X Wan, Y Wu, Q Zou, B Yuan, L Huang, M Hu - Epilepsy & Behavior, 2024‏ - Elsevier
Objective This review aims to summarize existing evidence on the adverse pregnancy
outcomes and seizure control effects of using lamotrigine (LTG) monotherapy in pregnancy …

Monotherapy treatment of epilepsy in pregnancy: congenital malformation outcomes in the child

R Bromley, N Adab, M Bluett-Duncan… - Cochrane Database …, 2023‏ - cochranelibrary.com
Background Prenatal exposure to certain anti‐seizure medications (ASMs) is associated
with an increased risk of major congenital malformations (MCM). The majority of women with …

Effect of gabapentin on fetal rat brain and its amelioration by ginger

GM Badawy, MN Atallah, SA Sakr - Heliyon, 2019‏ - cell.com
Intrauterine exposure to antiepileptic drugs (AEDs) is associated with neurodevelopmental
alterations causing postnatal behavioral and cognitive alterations. These disorders are …

Fetal safety of levetiracetam use during pregnancy

G Koc, S Keskin Guler, O Karadas, T Yoldas… - Acta neurologica …, 2018‏ - Springer
The aim of this study is to evaluate the effect of levetiracetam treatment during pregnancy on
fetus.. The pregnant women with epilepsy (PWWE) who were exposed to levetiracetam …

Therapeutic levetiracetam monitoring during pregnancy:“Mind the gap”

M Berlin, D Barchel… - … advances in chronic …, 2019‏ - journals.sagepub.com
Background: Epilepsy is one of the most common chronic neurological conditions and its
treatment during pregnancy is challenging. Levetiracetam (LEV) is an antiepileptic …

Levetiracetam use during pregnancy in women with active epilepsy: a hospital-based, retrospective study from a tertiary care hospital in North Eastern India

SR Sharma, N Sharma, M Hussain, H Mobing… - Neurology …, 2021‏ - journals.lww.com
Background and Purpose: Epilepsy during pregnancy is a therapeutic challenge. Since the
1990s, the number of licensed antiepileptic drugs has substantially increased, but safety …