Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …

Clonidine has proved to be a clinically useful adjunct in clinical anaesthetic practice as well
as in chronic pain therapy because it has both anaesthetic and analgesic‐sparing activity …

Abstract▴ Dexmedetomidine is a potent α 2-adrenoceptor agonist with 8 times higher affinity
for the α 2-adrenoceptorthan clonidine.▴ Dexmedetomidine has shown sedative, analgesic …

Alpha (α)-2-Adrenergic receptor (AR) agonists have been the focus of interest for their
sedative, analgesic, perioperative sympatholytic, anesthetic-sparing, and hemodynamic …

The hemodynamic response to the stress of laryngoscopy and endotracheal intubation does
not present a problem for most patients. However, patients with cardiovascular or cerebral …

We tested dexmedetomidine, an α 2 agonist that decreases heart rate, blood pressure, and
plasma norepinephrine concentration, for its ability to attenuate stress responses during …

Objective: To review recent literature on the safety and efficacy of dexmedetomidine. Data
Sources: Articles were identified through searches of MEDLINE (1966–January 2007). Key …

BACKGROUND: Dexmedetomidine (Dex), an α 2 agonist, has well-known anesthetic and
analgesic-sparing effects. We designed this prospective, randomized, double-blind, and …

IMPLICATIONS: This study was designed to evaluate the effect of dexmedetomidine when
added to lidocaine for IV regional anesthesia. This is the first clinical study demonstrating …

Background: Dexmedetomidine, an α-2 adrenoreceptor agonist, is gaining popularity for its
sympatholytic, sedative, anaesthetic sparing and haemodynamic stabilising properties …