Objective To provide an overview of filaggrin biology and the role of filaggrin variants in
atopic dermatitis (AD) and allergic disease. Data Sources We performed a PubMed literature …

Progress in the diagnosis of leishmaniases depends on the development of effective
methods and the discovery of suitable biomarkers. We propose firstly an update …

Genoty** by sequencing (GBS) is a next generation sequencing based method that takes
advantage of reduced representation to enable high throughput genoty** of large …

We introduce a flexible and robust simulation-based framework to infer demographic
parameters from the site frequency spectrum (SFS) computed on large genomic datasets …

In a pair of seminal papers, Sewall Wright and Gustave Malécot introduced F ST as a
measure of structure in natural populations. In the decades that followed, a number of …

One enduring question in evolutionary biology is the extent of archaic admixture in the
genomes of present-day populations. In this paper, we present a test for ancient admixture …

The past fifty years have seen the development and application of numerous statistical
methods to identify genomic regions that appear to be shaped by natural selection. These …

We describe 2b-RAD, a streamlined restriction site–associated DNA (RAD) genoty**
method based on sequencing the uniform fragments produced by type IIB restriction …

Background Genoty** by sequencing, a new low-cost, high-throughput sequencing
technology was used to genotype 2,815 maize inbred accessions, preserved mostly at the …

Demographic models built from genetic data play important roles in illuminating prehistorical
events and serving as null models in genome scans for selection. We introduce an inference …