Damage-associated molecular patterns (DAMPs) are endogenous danger molecules that
are released from damaged or dying cells and activate the innate immune system by …

Alzheimer disease (AD) is the most common type of dementia, and is currently incurable;
existing treatments for AD produce only a modest amelioration of symptoms. Research into …

The prevalence of cerebrovascular disease increases with age, placing the elderly at a
greater lifetime risk for dementia. Vascular cognitive impairment (VCI) encompasses a …

The S100 family of proteins contains 25 known members that share a high degree of
sequence and structural similarity. However, only a limited number of family members have …

Astrocytic contributions to Alzheimer's disease (AD) progression were, until recently, largely
overlooked. Astrocytes are integral to normal brain function and astrocyte reactivity is an …

Alzheimer's disease (AD) is a debilitating neurological disorder, and currently, there is no
cure for it. Several pathologic alterations have been described in the brain of AD patients …

Objective To perform a systematic review and meta-analysis to determine whether fluid and
imaging astrocyte biomarkers are altered in Alzheimer disease (AD). Methods PubMed and …

Neurodegeneration is a complex process that leads to irreversible neuronal damage and
death in spinal cord injury (SCI) and various neurodegenerative diseases, which are …

S100 proteins are calcium-binding proteins that regulate several processes associated with
Alzheimer's disease (AD) but whose contribution and direct involvement in disease …

Pathogen-associated molecular patterns (PAMPs) and endogenous “danger” signals,
known as danger-associated molecular patterns (DAMPs), released from cells alert the …