Neuronal circuits for fear and anxiety

P Tovote, JP Fadok, A Lüthi - Nature Reviews Neuroscience, 2015 - nature.com
Decades of research has identified the brain areas that are involved in fear, fear extinction,
anxiety and related defensive behaviours. Newly developed genetic and viral tools …

Amygdala microcircuits controlling learned fear

S Duvarci, D Pare - Neuron, 2014 - cell.com
We review recent work on the role of intrinsic amygdala networks in the regulation of
classically conditioned defensive behaviors, commonly known as conditioned fear. These …

Plastic synaptic networks of the amygdala for the acquisition, expression, and extinction of conditioned fear

HC Pape, D Pare - Physiological reviews, 2010 - journals.physiology.org
The last 10 years have witnessed a surge of interest for the mechanisms underlying the
acquisition and extinction of classically conditioned fear responses. In part, this results from …

[HTML][HTML] Amygdala inhibitory circuits and the control of fear memory

I Ehrlich, Y Humeau, F Grenier, S Ciocchi, C Herry… - Neuron, 2009 - cell.com
Classical fear conditioning is a powerful behavioral paradigm that is widely used to study the
neuronal substrates of learning and memory. Previous studies have clearly identified the …

Amygdala interneuron subtypes control fear learning through disinhibition

SBE Wolff, J Gründemann, P Tovote, S Krabbe… - Nature, 2014 - nature.com
Learning is mediated by experience-dependent plasticity in neuronal circuits. Activity in
neuronal circuits is tightly regulated by different subtypes of inhibitory interneurons, yet their …

From structure to behavior in basolateral amygdala-hippocampus circuits

Y Yang, JZ Wang - Frontiers in neural circuits, 2017 - frontiersin.org
Emotion influences various cognitive processes, including learning and memory. The
amygdala is specialized for input and processing of emotion, while the hippocampus is …

Basolateral amygdala and stress-induced hyperexcitability affect motivated behaviors and addiction

BM Sharp - Translational psychiatry, 2017 - nature.com
The amygdala integrates and processes incoming information pertinent to reward and to
emotions such as fear and anxiety that promote survival by warning of potential danger …

Memories are not written in stone: Re-writing fear memories by means of non-invasive brain stimulation and optogenetic manipulations

S Borgomaneri, S Battaglia, G Sciamanna… - Neuroscience & …, 2021 - Elsevier
The acquisition of fear associative memory requires brain processes of coordinated neural
activity within the amygdala, prefrontal cortex (PFC), hippocampus, thalamus and brainstem …

Sex differences in fear responses: Neural circuits

EP Bauer - Neuropharmacology, 2023 - Elsevier
Women have increased vulnerability to PTSD and anxiety disorders compared to men.
Understanding the neurobiological underpinnings of these disorders is critical for identifying …

Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response

MN Hill, RJ McLaughlin, B Pan… - Journal of …, 2011 - Soc Neuroscience
The mechanisms subserving the ability of glucocorticoid signaling within the medial
prefrontal cortex (mPFC) to terminate stress-induced activation of the hypothalamic–pituitary …