AMPK: guardian of metabolism and mitochondrial homeostasis
Cells constantly adapt their metabolism to meet their energy needs and respond to nutrient
availability. Eukaryotes have evolved a very sophisticated system to sense low cellular ATP …
availability. Eukaryotes have evolved a very sophisticated system to sense low cellular ATP …
[HTML][HTML] Exercise, GLUT4, and skeletal muscle glucose uptake
EA Richter, M Hargreaves - Physiological reviews, 2013 - journals.physiology.org
Glucose is an important fuel for contracting muscle, and normal glucose metabolism is vital
for health. Glucose enters the muscle cell via facilitated diffusion through the GLUT4 glucose …
for health. Glucose enters the muscle cell via facilitated diffusion through the GLUT4 glucose …
Exercise-stimulated glucose uptake—regulation and implications for glycaemic control
Skeletal muscle extracts glucose from the blood to maintain demand for carbohydrates as an
energy source during exercise. Such uptake involves complex molecular signalling …
energy source during exercise. Such uptake involves complex molecular signalling …
[HTML][HTML] AMPK in skeletal muscle function and metabolism
Skeletal muscle possesses a remarkable ability to adapt to various physiologic conditions.
AMPK is a sensor of intracellular energy status that maintains energy stores by fine-tuning …
AMPK is a sensor of intracellular energy status that maintains energy stores by fine-tuning …
[HTML][HTML] Global phosphoproteomic analysis of human skeletal muscle reveals a network of exercise-regulated kinases and AMPK substrates
Exercise is essential in regulating energy metabolism and whole-body insulin sensitivity. To
explore the exercise signaling network, we undertook a global analysis of protein …
explore the exercise signaling network, we undertook a global analysis of protein …
The regulation of fat metabolism during aerobic exercise
Since the lipid profile is altered by physical activity, the study of lipid metabolism is a
remarkable element in understanding if and how physical activity affects the health of both …
remarkable element in understanding if and how physical activity affects the health of both …
Exercise and type 2 diabetes: molecular mechanisms regulating glucose uptake in skeletal muscle
KI Stanford, LJ Goodyear - Advances in physiology …, 2014 - journals.physiology.org
Exercise is a well-established tool to prevent and combat type 2 diabetes. Exercise improves
whole body metabolic health in people with type 2 diabetes, and adaptations to skeletal …
whole body metabolic health in people with type 2 diabetes, and adaptations to skeletal …
Tuning fatty acid oxidation in skeletal muscle with dietary fat and exercise
Both the consumption of a diet rich in fatty acids and exercise training result in similar
adaptations in several skeletal muscle proteins. These adaptations are involved in fatty acid …
adaptations in several skeletal muscle proteins. These adaptations are involved in fatty acid …
The role of AMPK in the regulation of skeletal muscle size, hypertrophy, and regeneration
DM Thomson - International journal of molecular sciences, 2018 - mdpi.com
AMPK (5'-adenosine monophosphate-activated protein kinase) is heavily involved in
skeletal muscle metabolic control through its regulation of many downstream targets …
skeletal muscle metabolic control through its regulation of many downstream targets …
Molecular regulation of fatty acid oxidation in skeletal muscle during aerobic exercise
This review summarizes how fatty acid (FA) oxidation is regulated in skeletal muscle during
exercise. From the available evidence it seems that acetyl-CoA availability in the …
exercise. From the available evidence it seems that acetyl-CoA availability in the …