[PDF][PDF] RETRACTED: Dysregulation of Survivin-Targeting microRNAs in Autoimmune Diseases: New Perspectives for Novel Therapies

N Shomali, M Suliman Maashi, B Baradaran… - Frontiers in …, 2022 - frontiersin.org
It has been well established that the etiopathogenesis of diverse autoimmune diseases is
rooted in the autoreactive immune cells' excessively proliferative state and impaired …

Multiple functions and regulatory network of miR-150 in B lymphocyte-related diseases

YZ Hu, Q Li, PF Wang, XP Li, ZL Hu - Frontiers in Oncology, 2023 - frontiersin.org
MicroRNAs (miRNAs) play vital roles in the post-transcriptional regulation of gene
expression. Previous studies have shown that miR-150 is a crucial regulator of B cell …

Survivin a pivotal antiapoptotic protein in rheumatoid arthritis

P Zafari, A Rafiei, SA Esmaeili… - Journal of cellular …, 2019 - Wiley Online Library
Rheumatoid arthritis (RA) is an autoimmune disease, pathologically characterized by
lymphocyte infiltration of the synovial membrane that leads to chronic inflammation and …

Optical biosensors for the detection of rheumatoid arthritis (RA) biomarkers: a comprehensive review

JJ Imas, C Ruiz Zamarreno, P Zubiate… - Sensors, 2020 - mdpi.com
A comprehensive review of optical biosensors for the detection of biomarkers associated
with rheumatoid arthritis (RA) is presented here, including microRNAs (miRNAs), C-reactive …

Altered expression of apoptosis‐related genes in rheumatoid arthritis peripheral blood mononuclear cell and related miRNA regulation

H Ebrahimian, M Akhtari, M Akhlaghi… - Immunity …, 2023 - Wiley Online Library
Aim Impaired apoptosis and proliferation resulted in autoreactive lymphocyte development
and inflammation in Rheumatoid arthritis (RA). TP53, BAX, FOXO1, and RB1 are related …

Survivin; a novel therapeutic target that correlates with survival of autoreactive T lymphocytes obtained from patients with ankylosing spondylitis

N Shomali, B Baradaran, AD Sorkhabi, A Sarkesh… - Gene, 2022 - Elsevier
Ankylosing spondylitis (AS) is progressive immune-mediated arthritis. Persistent
autoreactivity of T cells with an up-regulated Survivin expression is strongly implicated in AS …

Sodium propionate improves rheumatoid arthritis by inhibiting survivin mediated proliferation of fibroblast like synoviocytes by promoting miR-140-5p

S Ma, J Wang, F He, D Zuo, F Li, H Fan, Z Yin… - …, 2022 - Taylor & Francis
Background Increased proliferation and impaired death of fibroblast-like synovial cells play
an important role in the development of rheumatoid arthritis (RA). Survivin plays an …

Identification of key genes in non-small cell lung cancer by bioinformatics analysis

L Zhang, R Peng, Y Sun, J Wang, X Chong, Z Zhang - PeerJ, 2019 - peerj.com
Background Non-small cell lung cancer (NSCLC) is one of the most common malignant
tumors in the world, and it has become the leading cause of death of malignant tumors …

Development of an induced pluripotent stem cell–specific microRNA assay for detection of residual undifferentiated cells in natural killer cell therapy products

L Chung, LA Cogburn, L Sui, JL Dashnau - Cytotherapy, 2022 - Elsevier
Most clinically evaluated chimeric antigen receptor (CAR)-based cell therapies are
generated from autologous immune cells. However, there are several limitations to …

MicroRNA-106b overexpression suppresses synovial inflammation and alleviates synovial damage in patients with rheumatoid arthritis

L Liu, H Chen, T Jiang, D He - Modern Rheumatology, 2022 - academic.oup.com
Objectives To explore the effect of miR-106b on synovial inflammation and damage in
rheumatoid arthritis (RA) patients and further to investigate its possible mechanism. Methods …