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Consequences of adolescent drug use
MR Steinfeld, MM Torregrossa - Translational psychiatry, 2023 - nature.com
Substance use in adolescence is a known risk factor for the development of neuropsychiatric
and substance use disorders in adulthood. This is in part due to the fact that critical aspects …
and substance use disorders in adulthood. This is in part due to the fact that critical aspects …
Women are taking the hit: examining the unique consequences of cannabis use across the female lifespan
Cannabis use has risen dramatically in recent years due to global decriminalization and a
resurgence in the interest of potential therapeutic benefits. While emerging research is …
resurgence in the interest of potential therapeutic benefits. While emerging research is …
Metabotropic NMDAR Signaling Contributes to Sex Differences in Synaptic Plasticity and Episodic Memory
NMDA receptor (NMDAR)-mediated calcium influx triggers the induction and initial
expression of long-term potentiation (LTP). Here we report that in male rodents, ion flux …
expression of long-term potentiation (LTP). Here we report that in male rodents, ion flux …
The effect of traumatic brain injury on learning and memory: A synaptic focus
E Eyolfson, KRB Suesser, H Henry… - The …, 2024 - journals.sagepub.com
Deficits in learning and memory are some of the most commonly reported symptoms
following a traumatic brain injury (TBI). We will examine whether the neural basis of these …
following a traumatic brain injury (TBI). We will examine whether the neural basis of these …
Neural basis of adolescent THC-induced potentiation of opioid responses later in life
E Hubbard, P Derdeyn, VM Galinato, A Wu… - …, 2024 - nature.com
Use of one addictive drug typically influences the behavioral response to other drugs, either
administered at the same time or a subsequent time point. The nature of the drugs being …
administered at the same time or a subsequent time point. The nature of the drugs being …
Adolescent THC impacts on mPFC dopamine-mediated cognitive processes in male and female rats
Rationale Adolescent cannabis use is linked to later-life changes in cognition, learning, and
memory. Rodent experimental studies suggest Δ9-tetrahydrocannabinol (THC) influences …
memory. Rodent experimental studies suggest Δ9-tetrahydrocannabinol (THC) influences …
Sex differences in the context dependency of episodic memory
Context contributes to multiple aspects of human episodic memory including segmentation
and retrieval. The present studies tested if, in adult male and female mice, context influences …
and retrieval. The present studies tested if, in adult male and female mice, context influences …
Pre-versus post-synaptic forms of LTP in two branches of the same hippocampal afferent
J Quintanilla, Y Jia, BS Pruess, J Chavez… - Journal of …, 2024 - jneurosci.org
There has been considerable controversy about pre-versus postsynaptic expression of
memory-related long-term potentiation (LTP), with corresponding disputes about underlying …
memory-related long-term potentiation (LTP), with corresponding disputes about underlying …
Postnatal GABAA Receptor Activation Alters Synaptic Plasticity and Cognition in Adult Wistar Rats
M Amani, F Mohammadian, N Golitabari… - Molecular …, 2022 - Springer
Early life alteration in the activity of gamma-aminobutyric acid (GABA) receptors is
associated with long-lasting developmental effects on the brain and behavior. GABAA …
associated with long-lasting developmental effects on the brain and behavior. GABAA …
Metabotropic NMDA Receptor Signaling Contributes to Sex Differences in Synaptic Plasticity and Episodic Memory
Men generally outperform women on encoding spatial components of episodic memory
whereas the reverse holds for semantic elements. Here we show that female mice …
whereas the reverse holds for semantic elements. Here we show that female mice …