Microglia, the resident immune cells in the brain, are essential for modulating neurogenesis,
influencing synaptic remodeling, and regulating neuroinflammation by surveying the brain …

The use of the diffusion tensor imaging (DTI) is rapidly growing in the neuroimaging field.
Nevertheless, rigorously performed quantitative validation of DTI pathologic metrics remains …

Psychiatric sequelae substantially contribute to the post-acute burden of disease associated
with COVID-19, persisting months after clearance of the virus. Brain imaging shows white …

Parkinson's disease (PD) is the second most common neurodegenerative disease after
Alzheimer's disease (AD). It is characterized by a progressive loss of dopaminergic neurons …

The cuprizone mouse model allows the investigation of the complex molecular mechanisms
behind nonautoimmune-mediated demyelination and spontaneous remyelination. While it is …

Although connections between cognitive deficits and age-associated brain differences have
been elucidated, relationships with motor performance are less well understood. Here, we …

Diffusion tensor imaging (DTI) is a promising method for characterizing microstructural
changes or differences with neuropathology and treatment. The diffusion tensor may be …

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS).
Microglia are the resident innate immune cells in the CNS; they play an important role in the …

The brain contains more than 100 billion neurons that communicate with each other via
axons for the formation of complex neural networks. The structural map** of such …

In this article we review recent research on diffusion tensor imaging (DTI) of white matter
(WM) integrity and the implications for age-related differences in cognition. Neurobiological …