The human connectome in Alzheimer disease—relationship to biomarkers and genetics
The pathology of Alzheimer disease (AD) damages structural and functional brain networks,
resulting in cognitive impairment. The results of recent connectomics studies have now …
resulting in cognitive impairment. The results of recent connectomics studies have now …
ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries
This review summarizes the last decade of work by the ENIGMA (E nhancing N euro I
maging G enetics through M eta A nalysis) Consortium, a global alliance of over 1400 …
maging G enetics through M eta A nalysis) Consortium, a global alliance of over 1400 …
The future of rodent models in depression research
Currently, over 300 million people worldwide have depression, and the socioeconomic
burden of this debilitating disorder is anticipated to increase markedly over the coming …
burden of this debilitating disorder is anticipated to increase markedly over the coming …
Functional connectomics from resting-state fMRI
Spontaneous fluctuations in activity in different parts of the brain can be used to study
functional brain networks. We review the use of resting-state functional MRI (rfMRI) for the …
functional brain networks. We review the use of resting-state functional MRI (rfMRI) for the …
Long-term neural and physiological phenoty** of a single human
Psychiatric disorders are characterized by major fluctuations in psychological function over
the course of weeks and months, but the dynamic characteristics of brain function over this …
the course of weeks and months, but the dynamic characteristics of brain function over this …
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
Abstract The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA)
Consortium is a collaborative network of researchers working together on a range of large …
Consortium is a collaborative network of researchers working together on a range of large …
Novel drug developmental strategies for treatment‐resistant depression
Major depressive disorder is a leading cause of disability worldwide. Because conventional
therapies are ineffective in many patients, novel strategies are needed to overcome …
therapies are ineffective in many patients, novel strategies are needed to overcome …
The quest for identifiability in human functional connectomes
The evaluation of the individual “fingerprint” of a human functional connectome (FC) is
becoming a promising avenue for neuroscientific research, due to its enormous potential …
becoming a promising avenue for neuroscientific research, due to its enormous potential …
Genetic and phylogenetic uncoupling of structure and function in human transmodal cortex
Brain structure scaffolds intrinsic function, supporting cognition and ultimately behavioral
flexibility. However, it remains unclear how a static, genetically controlled architecture …
flexibility. However, it remains unclear how a static, genetically controlled architecture …
Brain imaging genomics: integrated analysis and machine learning
Brain imaging genomics is an emerging data science field, where integrated analysis of
brain imaging and genomics data, often combined with other biomarker, clinical, and …
brain imaging and genomics data, often combined with other biomarker, clinical, and …