[HTML][HTML] Update on prevalence and mechanisms of resistance to linezolid, tigecycline and daptomycin in enterococci in Europe: Towards a common nomenclature
Vancomycin-resistant enterococci (VRE) are important nosocomial pathogens. Invasive VRE
infections are difficult to treat since common therapeutic options including ampicillin and …
infections are difficult to treat since common therapeutic options including ampicillin and …
The action mechanism of daptomycin
SD Taylor, M Palmer - Bioorganic & medicinal chemistry, 2016 - Elsevier
Daptomycin is a lipopeptide antibiotic produced by the soil bacterium Streptomyces
roseosporus that is clinically used to treat severe infections with Gram-positive bacteria. In …
roseosporus that is clinically used to treat severe infections with Gram-positive bacteria. In …
A highly efficacious electrical biofilm treatment system for combating chronic wound bacterial infections
Biofilm infection has a high prevalence in chronic wounds and can delay wound healing.
Current treatment using debridement and antibiotic administration imposes a significant …
Current treatment using debridement and antibiotic administration imposes a significant …
Resistance in vancomycin-resistant enterococci
WR Miller, BE Murray, LB Rice… - Infectious Disease Clinics, 2020 - id.theclinics.com
The genus Enterococcus consists of facultative gram-positive cocci that have been isolated
from a variety of animals, plants, and environmental sources. Although 58 species have …
from a variety of animals, plants, and environmental sources. Although 58 species have …
Mechanisms of daptomycin resistance in Staphylococcus aureus: role of the cell membrane and cell wall
The bactericidal, cell membrane–targeting lipopeptide antibiotic daptomycin (DAP) is an
important agent in treating invasive Staphylococcus aureus infections. However, there have …
important agent in treating invasive Staphylococcus aureus infections. However, there have …
Daptomycin
Daptomycin is a cyclic lipopeptide antibiotic used for the treatment of Gram-positive
infections including complicated skin and skin structure infections, right-sided infective …
infections including complicated skin and skin structure infections, right-sided infective …
Mechanisms of drug resistance: daptomycin resistance
Daptomycin (DAP) is a cyclic lipopeptide with in vitro activity against a variety of Gram‐
positive pathogens, including multidrug‐resistant organisms. Since its introduction into …
positive pathogens, including multidrug‐resistant organisms. Since its introduction into …
Molecular engineering of antimicrobial peptides: Microbial targets, peptide motifs and translation opportunities
The global public health threat of antimicrobial resistance has led the scientific community to
highly engage into research on alternative strategies to the traditional small molecule …
highly engage into research on alternative strategies to the traditional small molecule …
Mechanism of action and resistance to daptomycin in Staphylococcus aureus and enterococci
Lipopeptides are natural product antibiotics that consist of a peptide core with a lipid tail with
a diverse array of target organisms and mechanisms of action. Daptomycin (DAP) is an …
a diverse array of target organisms and mechanisms of action. Daptomycin (DAP) is an …
A current perspective on daptomycin for the clinical microbiologist
RM Humphries, S Pollett… - Clinical microbiology …, 2013 - Am Soc Microbiol
Daptomycin is a lipopeptide antimicrobial with in vitro bactericidal activity against Gram-
positive bacteria that was first approved for clinical use in 2004 in the United States. Since …
positive bacteria that was first approved for clinical use in 2004 in the United States. Since …