Adrenal glucocorticoids are major modulators of multiple functions, including energy
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …

Most aspects of energy metabolism display clear variations during day and night. This daily
rhythmicity of metabolic functions, including hormone release, is governed by a circadian …

Objectives Understanding the molecular mechanisms underlying human cartilage
degeneration and regeneration is helpful for improving therapeutic strategies for treating …

Circadian rhythms are generated by the autonomous circadian clock, the suprachiasmatic
nucleus (SCN), and clock genes that are present in all tissues. The SCN times these …

Pathologies of central nervous system (CNS) functions are involved in prevalent conditions
such as Alzheimer's disease, depression, and Parkinson's disease. Notable pathologies …

Sleep is a physiological global state composed of two different phases: Non-rapid eye
movement (NREM) and rapid eye movement (REM) sleep. The control mechanisms of sleep …

Simple Summary Our daily life follows 24-h cycles in various biological functions, such as
sleep–wake and feeding/fasting cycles. These rhythms are regulated by endogenous clocks …

Objective To characterize the circadian clock in murine cartilage tissue and identify tissue‐
specific clock target genes, and to investigate whether the circadian clock changes during …

Circadian and homeostatic neural circuits organize the temporal architecture of physiology
and behavior, but knowledge of their interactions is imperfect. For example, neurons …

Exercise during the inactive period can entrain locomotor activity and peripheral circadian
clock rhythm in mice; however, mechanisms underlying this entrainment are yet to be …