Eltroxin and Hesperidin mitigate testicular and renal damage in hypothyroid rats: amelioration of oxidative stress through PPARγ and Nrf2/HO-1 signaling pathway

HM Osama, SM Khadrawy, ES El-Nahass… - Laboratory Animal …, 2024 - Springer
Abstract Background Thyroid hormones (THs) regulate growth, development and function of
different tissues. Hypothyroidism is a common clinical disorder characterized by deficiency …

Vitamin E prevented hepatic and renal tissue damage in hypothyroid rats

M Hedayati-Moghadam, Y Baghcheghi… - Advanced Biomedical …, 2023 - journals.lww.com
Background: Considering antioxidant effects of vitamin E (Vit E), in the present study, the
effect of Vit E on liver and kidney functions and oxidative stress parameters in tissues of …

N‑acetylcysteine prevents hypothyroidism‑induced impairment of learning and memory in adolescent male rats via affecting oxidative status, inflammatory response …

A Basiri, S Izadi, S Kakhki, V Alikahni, S Askarian… - Acta Neurobiologiae …, 2024 - ane.pl
The present study was assumed that N‑acetylcysteine (AC) might improve cognitive function
in adolescent rats with hypothyroidism through various mechanisms. Sixty adolescent rats …

Thymoquinone improved redox homeostasis in the heart and aorta of hypothyroid rats

Y Baghcheghi, F Beheshti, F Seyedi… - Clinical and …, 2022 - Taylor & Francis
Objectives Propylthiouracil (PTU) is a common drug that is used in medicine for treating
hyperthyroidism. Furthermore, hypothyroidism can also be induced with PTU. Considering …

The effects of pioglitazone and rosiglitazone on liver function in hypothyroid rats

Y Baghcheghi, F Beheshti, F Seyedi… - … of Complementary and …, 2024 - degruyter.com
Objectives This study aimed to investigate the antioxidant effect of rosiglitazone (ROG) and
pioglitazone (POG) on oxidative damage and dysfunction of hepatic tissue in hypothyroid …