Disease manifestations and pathogenic mechanisms of group A Streptococcus

MJ Walker, TC Barnett, JD McArthur… - Clinical microbiology …, 2014 - journals.asm.org
Streptococcus pyogenes, also known as group A Streptococcus (GAS), causes mild human
infections such as pharyngitis and impetigo and serious infections such as necrotizing …

Molecular basis of group A streptococcal virulence

AL Bisno, MO Brito, CM Collins - The Lancet infectious diseases, 2003 - thelancet.com
The group A streptococcus (GAS)(Streptococcus pyogenes) is among the most common and
versatile of human pathogens. It is responsible for a wide spectrum of human diseases …

Epidemiology of invasive group A streptococcal infections in the United States, 2005–2012

GE Nelson, T Pondo, KA Toews… - Reviews of Infectious …, 2016 - academic.oup.com
Abstract Background. Invasive group A Streptococcus (GAS) infections are associated with
significant morbidity and mortality rates. We report the epidemiology and trends of invasive …

2007 guideline for isolation precautions: preventing transmission of infectious agents in health care settings

JD Siegel, E Rhinehart, M Jackson… - American journal of …, 2007 - pmc.ncbi.nlm.nih.gov
Executive Summary The Guideline for Isolation Precautions: Preventing Transmission of
Infectious Agents in Health Care Settings 2007 updates and expands the 1996 Guideline for …

Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences

W Nasser, SB Beres, RJ Olsen, MA Dean… - Proceedings of the …, 2014 - pnas.org
We sequenced the genomes of 3,615 strains of serotype Emm protein 1 (M1) group A
Streptococcus to unravel the nature and timing of molecular events contributing to the …

The epidemiology of invasive group A streptococcal infection and potential vaccine implications: United States, 2000–2004

RE O'Loughlin, A Roberson, PR Cieslak… - Clinical Infectious …, 2007 - academic.oup.com
Abstract Background. Invasive group A Streptococcus (GAS) infection causes significant
morbidity and mortality in the United States. We report the current epidemiologic …

Epidemiology of Severe Streptococcus pyogenes Disease in Europe

TL Lamagni, J Darenberg, B Luca-Harari… - Journal of clinical …, 2008 - journals.asm.org
The past 2 decades have brought worrying increases in severe Streptococcus pyogenes
diseases globally. To investigate and compare the epidemiological patterns of these …

Effectiveness of clindamycin and intravenous immunoglobulin, and risk of disease in contacts, in invasive group a streptococcal infections

JR Carapetis, P Jacoby, K Carville… - Clinical infectious …, 2014 - academic.oup.com
Background. The use of clindamycin and intravenous immunoglobulin (IVIG) in treatment of
invasive group A streptococcal (iGAS) infection, and the need for prophylactic antibiotics in …

Galleria mellonella larvae as an infection model for group A streptococcus

JMS Loh, N Adenwalla, S Wiles, T Proft - Virulence, 2013 - Taylor & Francis
Group A streptococcus is a strict human pathogen that can cause a wide range of diseases,
such as tonsillitis, impetigo, necrotizing fasciitis, toxic shock, and acute rheumatic fever …

Invasive group a streptococcal disease: epidemiology, pathogenesis and management

AC Steer, T Lamagni, N Curtis, JR Carapetis - Drugs, 2012 - Springer
Invasive group A streptococcal infections are uncommon, although serious, infections with
high case fatality rates. Periodic resurgences in invasive group A streptococcal infections in …