Methodological quality (risk of bias) assessment tools for primary and secondary medical studies: what are they and which is better?

LL Ma, YY Wang, ZH Yang, D Huang, H Weng… - Military Medical …, 2020 - Springer
Methodological quality (risk of bias) assessment is an important step before study initiation
usage. Therefore, accurately judging study type is the first priority, and the choosing proper …

Acute pneumonia and the cardiovascular system

VF Corrales-Medina, DM Musher, S Shachkina… - The Lancet, 2013 - thelancet.com
Although traditionally regarded as a disease confined to the lungs, acute pneumonia has
important effects on the cardiovascular system at all severities of infection. Pneumonia tends …

[HTML][HTML] Rosuvastatin for sepsis-associated acute respiratory distress syndrome

TN Heart - The New England journal of medicine, 2014 - ncbi.nlm.nih.gov
BACKGROUND In the acute respiratory distress syndrome (ARDS), inflammation in the
lungs and other organs can cause life-threatening organ failure. Inhibitors of 3-hydroxy-3 …

Cardiac complications in patients with community-acquired pneumonia: incidence, timing, risk factors, and association with short-term mortality

VF Corrales-Medina, DM Musher, GA Wells… - Circulation, 2012 - Am Heart Assoc
Background—Community-acquired pneumonia (CAP) affects> 5 million adults each year in
the United States. Although incident cardiac complications occur in patients with community …

Testing the Newcastle Ottawa Scale showed low reliability between individual reviewers

L Hartling, A Milne, MP Hamm, B Vandermeer… - Journal of clinical …, 2013 - Elsevier
Objectives To assess inter-rater reliability and validity of the Newcastle Ottawa Scale (NOS)
used for methodological quality assessment of cohort studies included in systematic …

Cirrhosis as new indication for statins

J Bosch, J Gracia-Sancho, JG Abraldes - Gut, 2020 - gut.bmj.com
In the recent years, there have been an increasing number of reports on favourable effects of
statins in patients with advanced chronic liver disease. These include reduction in portal …

Effect of statin therapy on mortality in patients with ventilator-associated pneumonia: a randomized clinical trial

L Papazian, A Roch, PE Charles, C Penot-Ragon… - Jama, 2013 - jamanetwork.com
Importance Observational studies have reported that statin use may be associated with
improved outcomes of various infections. Ventilator-associated pneumonia (VAP) is the most …

[HTML][HTML] Simvastatin prevents progression of acute on chronic liver failure in rats with cirrhosis and portal hypertension

DM Tripathi, M Vilaseca, E Lafoz, H Garcia-Caldero… - Gastroenterology, 2018 - Elsevier
Background & Aims Cirrhosis and its clinical consequences can be aggravated by bacterial
infections, ultimately leading to the development of acute on chronic liver failure (ACLF) …

Rosuvastatin versus placebo for delirium in intensive care and subsequent cognitive impairment in patients with sepsis-associated acute respiratory distress …

DM Needham, E Colantuoni, VD Dinglas… - The lancet Respiratory …, 2016 - thelancet.com
Background Delirium is common in mechanically ventilated patients and is associated with
cognitive impairment lasting at least 1 year after hospital discharge. Preclinical and …

Pharmacological targeting of the host–pathogen interaction: alternatives to classical antibiotics to combat drug-resistant superbugs

J Munguia, V Nizet - Trends in Pharmacological Sciences, 2017 - cell.com
The rise of multidrug-resistant pathogens and the dearth of new antibiotic development
place an existential strain on successful infectious disease therapy. Breakthrough strategies …