Medial and orbital frontal cortex in decision-making and flexible behavior

MC Klein-Flügge, A Bongioanni, MFS Rushworth - Neuron, 2022 - cell.com
The medial frontal cortex and adjacent orbitofrontal cortex have been the focus of
investigations of decision-making, behavioral flexibility, and social behavior. We review …

The whole prefrontal cortex is premotor cortex

JM Fine, BY Hayden - Philosophical Transactions of the …, 2022 - royalsocietypublishing.org
We propose that the entirety of the prefrontal cortex (PFC) can be seen as fundamentally
premotor in nature. By this, we mean that the PFC consists of an action abstraction hierarchy …

[HTML][HTML] The neural basis of effort valuation: A meta-analysis of functional magnetic resonance imaging studies

P Lopez-Gamundi, YW Yao, TTJ Chong… - Neuroscience & …, 2021 - Elsevier
Choosing how much effort to expend is critical for everyday decisions. While several
neuroimaging studies have examined effort-based decision-making, results have been …

From exploration to exploitation: A shifting mental mode in late life development

RN Spreng, GR Turner - Trends in Cognitive Sciences, 2021 - cell.com
Changes in cognition, affect, and brain function combine to promote a shift in the nature of
mentation in older adulthood, favoring exploitation of prior knowledge over exploratory …

Understanding patch foraging strategies across development

A Lloyd, E Viding, R McKay, N Furl - Trends in Cognitive Sciences, 2023 - cell.com
Patch foraging is a near-ubiquitous behaviour across the animal kingdom and characterises
many decision-making domains encountered by humans. We review how a disposition to …

Choice-relevant information transformation along a ventrodorsal axis in the medial prefrontal cortex

DJN Maisson, TV Cash-Padgett, MZ Wang… - Nature …, 2021 - nature.com
Choice-relevant brain regions in prefrontal cortex may progressively transform information
about options into choices. Here, we examine responses of neurons in four regions of the …

Prefrontal cortex interactions with the amygdala in primates

EA Murray, LK Fellows - Neuropsychopharmacology, 2022 - nature.com
This review addresses functional interactions between the primate prefrontal cortex (PFC)
and the amygdala, with emphasis on their contributions to behavior and cognition. The …

Shifts in attention drive context-dependent subspace encoding in anterior cingulate cortex in mice during decision making

MA Hajnal, D Tran, Z Szabó, A Albert… - Nature …, 2024 - nature.com
Attention supports decision making by selecting the features that are relevant for decisions.
Selective enhancement of the relevant features and inhibition of distractors has been …

Representational spaces in orbitofrontal and ventromedial prefrontal cortex: task states, values, and beyond

N Moneta, S Grossman, NW Schuck - Trends in Neurosciences, 2024 - cell.com
The orbitofrontal cortex (OFC) and ventromedial-prefrontal cortex (vmPFC) play a key role in
decision-making and encode task states in addition to expected value. We review evidence …

Irrational choices via a curvilinear representational geometry for value

K Jurewicz, BJ Sleezer, PS Mehta, BY Hayden… - Nature …, 2024 - nature.com
We make decisions by comparing values, but it is not yet clear how value is represented in
the brain. Many models assume, if only implicitly, that the representational geometry of value …