Toxic effects of di‐2‐ethylhexyl phthalate: An overview

SSS Rowdhwal, J Chen - BioMed research international, 2018 - Wiley Online Library
Di‐2‐ethylhexyl phthalate (DEHP) is extensively used as a plasticizer in many products,
especially medical devices, furniture materials, cosmetics, and personal care products …

Effects of Di-2-ethylhexyl phthalate on central nervous system functions: a narrative review

S Safarpour, M Ghasemi-Kasman… - Current …, 2022 - benthamdirect.com
Background: Phthalates are widely used in the plastics industry. Di-2-Ethylhexyl Phthalate
(DEHP) is one of the most important phthalate metabolites that disrupt the function of …

Prenatal and breastfeeding exposure to low dose of diethylhexyl phthalate induces behavioral deficits and exacerbates oxidative stress in rat hippocampus

S Safarpour, E Zabihi, M Ghasemi-Kasman… - Food and Chemical …, 2021 - Elsevier
Diethylhexyl phthalate (DEHP) is one of the most important derivatives of phthalate that has
devastating effects on nervous system function. In this study, the effects of exposure with low …

Neural mechanisms underlying the disruption of male courtship behavior by adult exposure to di (2-ethylhexyl) phthalate in mice

C Dombret, D Capela, K Poissenot… - Environmental …, 2017 - ehp.niehs.nih.gov
Background: Courtship behavior plays a critical role in attracting females and reproduction
success. However, the effects of exposure to a ubiquitous contaminant di (2-ethylhexyl) …

Dose-dependent toxic effects of di-(2-ethylhexyl) phthalate in male rats: Focus on behavioral alterations and inducing TLR4/NF-κB signaling pathway

M Khalifa, RH Fayed, AA Sedik, HMA Khalil - Toxicology and Applied …, 2023 - Elsevier
Abstract Di-(2-ethylhexyl) phthalate (DEHP) is a widely used phthalate that possesses a
public health concern. Different concentrations of DEHP, including 50, 300, and 750 mg/kg …

Neural mechanisms underlying the deficit of learning and memory by exposure to Di (2-ethylhexyl) phthalate in rats

D Ran, Y Luo, Z Gan, J Liu, J Yang - Ecotoxicology and Environmental …, 2019 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP), as one of the most broadly representative
phthalic acid esters, is used as a plasticizer in Polyvinyl chloride production. The exact …

Metabolomic markers of phthalate exposure in plasma and urine of pregnant women

M Zhou, B Ford, D Lee, G Tindula, K Huen… - Frontiers in public …, 2018 - frontiersin.org
Phthalates are known endocrine disruptors and found in almost all people with several
associated adverse health outcomes reported in humans and animal models. Limited data …

Preadolescent phthalate (DEHP) exposure is associated with elevated locomotor activity and reward-related behavior and a reduced number of tyrosine hydroxylase …

MR Holahan, CA Smith, BE Luu… - Toxicological …, 2018 - academic.oup.com
Phthalate administration to male rats has been shown to negatively impact neural
development while development of the female rat brain is less affected. Because a number …

Brain lipid profiles in the spontaneously hypertensive rat after subchronic real-world exposure to ambient fine particulate matter

SH Lee, PH Lee, HJ Liang, CH Tang, TF Chen… - Science of The Total …, 2020 - Elsevier
Recent studies have illustrated an association between ambient fine particulate matter (PM
2.5) exposure and neuronal toxicity in epidemiological studies and animal models …

The roles of hippocampal microRNAs in response to acute postnatal exposure to di (2-ethylhexyl) phthalate in female and male rats

BE Luu, SR Green, CL Childers, MR Holahan… - Neurotoxicology, 2017 - Elsevier
Previous studies have shown that di (2-ethylhexyl) phthalate (DEHP) exposure impairs the
normal development of pre-and post-synaptic elements of the male, but not female, rat …