Deterministic lateral displacement: Challenges and perspectives

A Hochstetter, R Vernekar, RH Austin, H Becker… - ACS …, 2020 - ACS Publications
The advent of microfluidics in the 1990s promised a revolution in multiple industries from
healthcare to chemical processing. Deterministic lateral displacement (DLD) is a continuous …

A review of sorting, separation and isolation of cells and microbeads for biomedical applications: microfluidic approaches

A Dalili, E Samiei, M Hoorfar - Analyst, 2019 - pubs.rsc.org
Several biomedical analyses are performed on particular types of cells present in body
samples or using functionalized microparticles. Success in such analyses depends on the …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

A review on deterministic lateral displacement for particle separation and detection

T Salafi, Y Zhang, Y Zhang - Nano-Micro Letters, 2019 - Springer
The separation and detection of particles in suspension are essential for a wide spectrum of
applications including medical diagnostics. In this field, microfluidic deterministic lateral …

Advances in novel strategies for isolation, characterization, and analysis of CTCs and ctDNA

V Yaghoubi Naei, P Bordhan… - Therapeutic …, 2023 - journals.sagepub.com
Over the past decade, the detection and analysis of liquid biopsy biomarkers such as
circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) have advanced …

Microfluidic Label‐Free Hydrodynamic Separation of Blood Cells: Recent Developments and Future Perspectives

S Lee, H Kim, S Yang - Advanced Materials Technologies, 2023 - Wiley Online Library
The biophysical characteristics and counts of blood cells provide useful information
regarding pathological conditions. Therefore, the separation of blood components is a …

Passive microfluidic devices for cell separation

T Zhang, D Di Carlo, CT Lim, T Zhou, G Tian… - Biotechnology …, 2024 - Elsevier
The separation of specific cell populations is instrumental in gaining insights into cellular
processes, elucidating disease mechanisms, and advancing applications in tissue …

Progress of microfluidic continuous separation techniques for micro-/nanoscale bioparticles

S Choe, B Kim, M Kim - Biosensors, 2021 - mdpi.com
Separation of micro-and nano-sized biological particles, such as cells, proteins, and
nucleotides, is at the heart of most biochemical sensing/analysis, including in vitro …

Blood cell separation using polypropylene-based microfluidic devices based on deterministic lateral displacement

K Matsuura, K Takata - Micromachines, 2023 - mdpi.com
Mammalian blood cell separation methods contribute to improving the diagnosis and
treatment of animal and human diseases. Microfluidic deterministic lateral displacement …

Combination of microfluidic chips and biosensing for the enrichment of circulating tumor cells

J Shi, C Zhao, M Shen, Z Chen, J Liu, S Zhang… - Biosensors and …, 2022 - Elsevier
It has been reported that more than 90% of cancer patients are died from cancer metastasis.
Circulating tumor cells (CTCs) could detach from solid tumors to form new lesions via blood …