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[HTML][HTML] Advances in the stability challenges of bioactive peptides and improvement strategies
J Pei, X Gao, D Pan, Y Hua, J He, Z Liu… - Current Research in Food …, 2022 - Elsevier
Bioactive peptides are widely used in functional foods due to their remarkable efficacy,
selectivity, and low toxicity. However, commercially produced bioactive peptides lack quality …
selectivity, and low toxicity. However, commercially produced bioactive peptides lack quality …
Pro-angiogenic peptides in biomedicine
L De Rosa, R Di Stasi, LD D'Andrea - Archives of biochemistry and …, 2018 - Elsevier
Pro-angiogenic therapy provides a promising new perspective in tackling of many common
and severe pathological conditions, such as central and peripheral vascular diseases. Pro …
and severe pathological conditions, such as central and peripheral vascular diseases. Pro …
Conformational modulation and polymerization-induced folding of proteomimetic peptide brush polymers
Peptide-brush polymers generated by graft-through living polymerization of peptide-
modified monomers exhibit high proteolytic stability, therapeutic efficacy, and potential as …
modified monomers exhibit high proteolytic stability, therapeutic efficacy, and potential as …
Functional and pharmacological characterization of a VEGF mimetic peptide on reparative angiogenesis
F Finetti, A Basile, D Capasso, S Di Gaetano… - Biochemical …, 2012 - Elsevier
Vascular endothelial growth factor (VEGF) is the main regulator of physiological and
pathological angiogenesis. Low molecular weight molecules able to stimulate angiogenesis …
pathological angiogenesis. Low molecular weight molecules able to stimulate angiogenesis …
Poly (N-isopropylacrylamide)-based dual-crosslinking biohybrid injectable hydrogels for vascularization
Injectable hydrogels provide a powerful and non-invasive approach for numerous
applications in cell transplantation, growth factor delivery, tissue regeneration and so forth …
applications in cell transplantation, growth factor delivery, tissue regeneration and so forth …
Characterization of a designed vascular endothelial growth factor receptor antagonist helical peptide with antiangiogenic activity in vivo
Angiogenesis is a fundamental process underlining physiological and pathological
conditions. It is mainly regulated by the vascular endothelial growth factor (VEGF) and its …
conditions. It is mainly regulated by the vascular endothelial growth factor (VEGF) and its …
Structure-Based Design of Peptides Targeting VEGF/VEGFRs
R Di Stasi, L De Rosa, LD D'Andrea - Pharmaceuticals, 2023 - mdpi.com
Vascular endothelial growth factor (VEGF) and its receptors (VEGFRs) play a main role in
the regulation of angiogenesis and lymphangiogenesis. Furthermore, they are implicated in …
the regulation of angiogenesis and lymphangiogenesis. Furthermore, they are implicated in …
VEGFR recognition interface of a proangiogenic VEGF‐mimetic peptide determined in vitro and in the presence of endothelial cells by NMR spectroscopy
QK peptide is a vascular endothelial growth factor (VEGF)‐mimetic molecule with significant
proangiogenic activity. In particular, QK is able to bind and activate VEGF receptors …
proangiogenic activity. In particular, QK is able to bind and activate VEGF receptors …
[HTML][HTML] Substitution of the native Zn (II) with Cd (II), Co (II) and Ni (II) changes the downhill unfolding mechanism of Ros87 to a completely different scenario
The structural effects of zinc replacement by xenobiotic metal ions have been widely studied
in several eukaryotic and prokaryotic zinc-finger-containing proteins. The prokaryotic zinc …
in several eukaryotic and prokaryotic zinc-finger-containing proteins. The prokaryotic zinc …
β-hairpin peptide that targets vascular endothelial growth factor (VEGF) receptors: design, NMR characterization, and biological activity
VEGF receptors have been the target of intense research aimed to develop molecules able
to inhibit or stimulate angiogenesis. Based on the x-ray structure of the complex placental …
to inhibit or stimulate angiogenesis. Based on the x-ray structure of the complex placental …