[PDF][PDF] One year in review 2017: pathogenesis of rheumatoid arthritis

F Angelotti, A Parma, G Cafaro, R Capecchi… - Clin Exp …, 2017 - clinexprheumatol.org
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease influenced by both
genetic and environmental factors. It has been postulated that a high-risk genetic …

Angiogenesis as a potential treatment strategy for rheumatoid arthritis

Y Wang, H Wu, R Deng - European journal of pharmacology, 2021 - Elsevier
Angiogenesis is an early and key event in the pathogenesis of rheumatoid arthritis (RA) and
is crucial for the proliferation of synovial tissue and the formation of pannus. This process is …

Vascular endothelial growth factor (VEGF) as a vital target for brain inflammation during the COVID-19 outbreak

XX Yin, XR Zheng, W Peng, ML Wu… - ACS chemical …, 2020 - ACS Publications
The coronavirus disease 19 (COVID-19) pandemic has brought a great threat to global
public health. Currently, mounting evidence has shown the occurrence of neurological …

Human keratinocyte-derived microvesicle miRNA-21 promotes skin wound healing in diabetic rats through facilitating fibroblast function and angiogenesis

Q Li, H Zhao, W Chen, P Huang, J Bi - … journal of biochemistry & cell biology, 2019 - Elsevier
Skin wound healing is a complex physiological process that maintains the integrity of the
skin tissues, involving a variety of distinct cell types and signaling molecules. The specific …

[HTML][HTML] MicroRNAs in cancer metastasis and angiogenesis

W Lou, J Liu, Y Gao, G Zhong, D Chen, J Shen, C Bao… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Cancer metastasis is a malignant process by which tumor cells migrate from their primary
site of origin to other organs. It is the main cause of poor prognosis in cancer patients …

Interleukin‐35 in immune‐related diseases: protection or destruction

J Zhang, Y Zhang, Q Wang, C Li, H Deng, C Si… - …, 2019 - Wiley Online Library
Summary Interleukin‐35 (IL‐35) is a recently identified heterodimeric cytokine in the IL‐12
family. It consists of an IL‐12 subunit α chain (P35) and IL‐27 subunit Epstein–Barr virus …

Geniposide alleviates VEGF-induced angiogenesis by inhibiting VEGFR2/PKC/ERK1/2-mediated SphK1 translocation

Y Wang, H Wu, BJ Gui, J Liu, GX Rong, R Deng, YH Bu… - Phytomedicine, 2022 - Elsevier
Background Rheumatoid arthritis (RA) is an angiogenesis-dependent disease caused by
the imbalance of pro-and anti-angiogenic factors. More effective strategies to block synovial …

Emerging role of IL-35 in inflammatory autoimmune diseases

LC Su, XY Liu, AF Huang, WD Xu - Autoimmunity Reviews, 2018 - Elsevier
Abstract Interleukin 35 (IL-35) is the recently identified member of the IL-12 family of
cytokines and provides the possibility to be a target for new therapies for autoimmune …

Pathogenesis and function of interleukin-35 in rheumatoid arthritis

PL **n, LF Jie, Q Cheng, DY Bin… - Frontiers in Pharmacology, 2021 - frontiersin.org
It is well known that RA (Rheumatoid arthritis) is an autoimmune disease characterized by
multiple and symmetric arthropathy. The main pathological features of RA are synovial …

Interleukin‐35 regulates the balance of Th17 and Treg responses during the pathogenesis of connective tissue diseases

D Wang, L Lei - International journal of rheumatic diseases, 2021 - Wiley Online Library
Abstract Interleukin (IL)‐35 belongs to the IL‐12 cytokine family and is a heterodimer of the
p35 and Epstein‐Barr virus‐induced gene 3 (EBI3) subunits. Functionally, IL‐35 can …