Diabetic wound-healing science

JL Burgess, WA Wyant, B Abdo Abujamra, RS Kirsner… - Medicina, 2021 - mdpi.com
Diabetes mellitus is an increasingly prevalent chronic metabolic disease characterized by
prolonged hyperglycemia that leads to long-term health consequences. It is estimated that …

Hydrogel wound dressings for diabetic foot ulcer treatment: status‐quo, challenges, and future perspectives

A Ko, C Liao - BMEMat, 2023 - Wiley Online Library
Diabetic foot ulcers (DFU) are a common and often debilitating complication of diabetes that
can result in lower limb amputations if left untreated. Hydrogel dressings are three …

Construction of multifunctional wound dressings with their application in chronic wound treatment

L Long, W Liu, C Hu, L Yang, Y Wang - Biomaterials science, 2022 - pubs.rsc.org
As the prevalence of diabetes increases year by year and the aging population continues to
intensify in the world, chronic wounds such as diabetic foot ulcers and pressure ulcers have …

[HTML][HTML] Engineering homologous platelet-rich plasma, platelet-rich plasma-derived exosomes, and mesenchymal stem cell-derived exosomes-based dual …

BM Bakadia, AAQ Ahmed, L Lamboni, Z Shi… - Bioactive Materials, 2023 - Elsevier
The management of diabetic wounds remains a critical therapeutic challenge. Platelet-rich
plasma (PRP) gel, PRP-derived exosomes (PRP-Exos), and mesenchymal stem cell-derived …

Enhancing diabetic wound healing: Advances in electrospun scaffolds from pathogenesis to therapeutic applications

X Jiang, YE Zeng, C Li, K Wang, DG Yu - Frontiers in Bioengineering …, 2024 - frontiersin.org
Diabetic wounds are a significant subset of chronic wounds characterized by elevated levels
of inflammatory cytokines, matrix metalloproteinases (MMPs), and reactive oxygen species …

[HTML][HTML] Phytoconstituents as modulators of NF-κB signalling: Investigating therapeutic potential for diabetic wound healing

JP Yadav, A Verma, P Pathak, AR Dwivedi… - Biomedicine & …, 2024 - Elsevier
The NF-κB pathway plays a pivotal role in impeding the diabetic wound healing process,
contributing to prolonged inflammation, diminished angiogenesis, and reduced proliferation …

Translating clinical delineation of diabetic foot ulcers into machine interpretable segmentation

C Kendrick, B Cassidy, JM Pappachan… - Diabetic Foot Ulcers …, 2024 - Springer
Diabetic foot ulcer (DFU) is a severe condition that requires close monitoring and
management. Experienced clinical staff are best-positioned to provide ground truth …

3D bioprinted scaffolds for diabetic wound-healing applications

K Glover, E Mathew, G Pitzanti, E Magee… - Drug delivery and …, 2023 - Springer
The treatment strategy required for the effective healing of diabetic foot ulcer (DFU) is a
complex process that is requiring several combined therapeutic approaches. As a result …

Recent advances in electrospun nanofiber-based strategies for diabetic wound healing application

K Li, Z Zhu, Y Zhai, S Chen - Pharmaceutics, 2023 - mdpi.com
Diabetic ulcers are the second largest complication caused by diabetes mellitus. A great
number of factors, including hyperchromic inflammation, susceptible microbial infection …

Electrospun membranes chelated by metal magnesium ions enhance pro-angiogenic activity and promote diabetic wound healing

M Liu, X Wang, B Sun, H Wang, X Mo… - International Journal of …, 2024 - Elsevier
Diabetic wounds, resulting from skin atrophy due to localized ischemia and hypoxia in
diabetic patients, lead to chronic pathological inflammation and delayed healing. Using …